Rtecs number : ww2710000 chemical name : Talc (powder), containing no asbestos fibers

TANTALUM PENTOXIDE

CHEMICAL NAME : Tantalum oxide

CAS REGISTRY NUMBER : 1314-61-0

LAST UPDATED : 199907

DATA ITEMS CITED : 12

MOLECULAR FORMULA : O5-Ta2

MOLECULAR WEIGHT : 441.90

WISWESSER LINE NOTATION : TA2 O5

SYNONYMS/TRADE NAMES :

* Tantalic acid anhydride

* Tantalum oxide

* Tantalum penta oxide

* Tantalum pentoxide

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 8 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

EQSSDX Environmental Quality and Safety, Supplement. (Stuttgart, Fed.

Rep.

TYPE OF TEST : LD - Lethal dose

ROUTE OF EXPOSURE : Intraperitoneal

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : >5 gm/kg

TOXIC EFFECTS :

Vascular - regional or general arteriolar or venous dilation

Liver - other changes

Blood - other changes

REFERENCE :

INMEAF Industrial Medicine. (Chicago, IL) V.1-18, 1932-49. For

publisher

information, see IOHSA5. Volume(issue)/page/year: 15,482,1946

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - mouse

DOSE/DURATION : >4 gm/kg

TOXIC EFFECTS :

Behavioral - muscle contraction or spasticity

Lungs, Thorax, or Respiration - acute pulmonary edema

Liver - hepatitis (hepatocellular necrosis), diffuse

REFERENCE :

HYSAAV Hygiene and Sanitation (USSR). English translation of GISAAA.

(Springfield, VA) 1964-71. Discontinued. Volume(issue)/page/year:

32(10-12),343,1967

*** REVIEWS ***

ACGIH TLV-TWA 5 mg(Ta)/m3, dust

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

TLV/BEI,1997

ACGIH TLV-TWA 5mg(Ta)/m3, dust

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

TLV/BEI,1997

*** U.S. STANDARDS AND REGULATIONS ***

OSHA PEL (Gen Indu):8H TWA 5 mg/m3, dust

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

29,1910.1000,1994

OSHA PEL (Construc):8H TWA 5 mg/m3, dust

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

of Documents, Washington, DC 20402) Volume(issue)/page/year:

OSHA PEL (Shipyard):8H TWA 5 mg/m3, dust

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

29,1915.1000,1993

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-DENMARK: TWA 5 mg(Ta)/m3, JAN1999

OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV

OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

TARTARIC ACID

CHEMICAL NAME : Tartaric acid

CAS REGISTRY NUMBER : 87-69-4

OTHER CAS REGISTRY NOS. : 8014-54-8

8059-77-6

1336-18-1

LAST UPDATED : 199903

DATA ITEMS CITED : 7

MOLECULAR FORMULA : C4-H6-O6

MOLECULAR WEIGHT : 150.10

WISWESSER LINE NOTATION : QVYQYQVQ

COMPOUND DESCRIPTOR : Drug

SYNONYMS/TRADE NAMES :

* Butanedioic acid, 2,3-dihydroxy-

* Dextrotartaric acid

* 2,3-Dihydrosuccinic acid

* 2,3-Dihydroxybutanedioic acid

* 1,2-Dihydroxyethane-1,2-dicarboxylic acid

* d-alpha,beta-Dihydroxysuccinic acid

* Kyselina 2,3-dihydroxybutandiova

* Kyselina vinna

* Malic acid, 3-hydroxy-

* Succinic acid, 2,3-dihydroxy-

* Threaric acid

* (+)-Tartaric acid

* (+)-L-Tartaric acid

* (+)-(R,R)-Tartaric acid

* d-Tartaric acid

* L-Tartaric acid

* L-(+)-Tartaric acid

* (R,R)-(+)-Tartaric acid

* (2R,3R)-(+)-Tartaric acid

* (R,R)-Tartaric acid

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intravenous

SPECIES OBSERVED : Rodent - mouse

DOSE/DURATION : 485 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold

Blood - hemorrhage

REFERENCE :

JAFCAU Journal of Agricultural and Food Chemistry. (American Chemical

Soc.,

Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC

TYPE OF TEST : LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Mammal - dog

DOSE/DURATION : 5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JAPMA8 Journal of the American Pharmaceutical Association, Scientific

Edition. (Washington, DC) V.29-49, 1940-60. For publisher information,

see

JPMSAE. Volume(issue)/page/year: 39,275,1950

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : 5 gm/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

REFERENCE :

IECHAD Industrial and Engineering Chemistry. (Washington, DC) V.15-62,

1923-70. For publisher information, see CHMTBL.

Volume(issue)/page/year:

15,628,1923

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - X4599

No. of Facilities: 1626 (estimated)

No. of Industries: 25

No. of Occupations: 25

No. of Employees: 26774 (estimated)

No. of Female Employees: 5527 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1999