Rtecs number : ww2710000 chemical name : Talc (powder), containing no asbestos fibers

TELLURIUM

CHEMICAL NAME : Tellurium

CAS REGISTRY NUMBER : 13494-80-9

OTHER CAS REGISTRY NOS. : 137322-20-4

LAST UPDATED : 199907

DATA ITEMS CITED : 39

MOLECULAR FORMULA : Te

MOLECULAR WEIGHT : 127.60

WISWESSER LINE NOTATION : TE

COMPOUND DESCRIPTOR : Reproductive Effector

SYNONYMS/TRADE NAMES :

* NCI-C60117

* Telloy

* Tellur

* Tellurium element

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : >5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

TNONF* TNO-report. (TNO Nutrition and Food Research, P.O. Box 360, 3700

AJ

Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands)

TNO-91-063

TYPE OF TEST : LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE : Inhalation

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : >2420 mg/m3/4H

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes

Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

TNONF* TNO-report. (TNO Nutrition and Food Research, P.O. Box 360, 3700

AJ

Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands)

TNO-92-008

TYPE OF TEST : LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE : Intratracheal

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 200 mg/kg

TOXIC EFFECTS :

Lungs, Thorax, or Respiration - other changes

Liver - other changes

Kidney, Ureter, Bladder - other changes

REFERENCE :

AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf

Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year:

39,100,1978

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - mouse

DOSE/DURATION : >5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

TNONF* TNO-report. (TNO Nutrition and Food Research, P.O. Box 360, 3700

AJ

Zeist, Utrechtseweg 48, 3704 HE Zeist, Netherlands)

TNO-91-O64

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : 67 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under

Single

Exposure," Izmerov, N.F., et al., Moscow, Centre of International

GKNT, 1982 Volume(issue)/page/year: -,107,1982

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - guinea pig

DOSE/DURATION : 45 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under

Single

Exposure," Izmerov, N.F., et al., Moscow, Centre of International

GKNT, 1982 Volume(issue)/page/year: -,107,1982

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE : 3300 mg/kg

SEX/DURATION : female 1-22 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - Central Nervous

System

REFERENCE :

Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 31,1,1971

TYPE OF TEST : TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE : 1693 mg/kg

SEX/DURATION : female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - craniofacial

(including nose and tongue)

Reproductive - Specific Developmental Abnormalities - musculoskeletal

system

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.

First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information,

see TOSCF2 Volume(issue)/page/year: 11,691,1988

TYPE OF TEST : TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE : 6064 mg/kg

SEX/DURATION : female 6-15 day(s) after conception

TOXIC EFFECTS :

Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,

e.g., stunted fetus)

Reproductive - Specific Developmental Abnormalities - musculoskeletal

system

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E.

First St., Duluth, MN 55802) V.1-40, 1981-97. For publisher information,

see TOSCF2 Volume(issue)/page/year: 11,691,1988

TYPE OF TEST : TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE : Intramuscular

SPECIES OBSERVED : Rodent - rat

DOSE : 13 mg/kg

SEX/DURATION : female 10 day(s) after conception

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or

resorbed implants per total number of implants)

Reproductive - Specific Developmental Abnormalities - Central Nervous

System

REFERENCE :

Switzerland) V.1- 1945- Volume(issue)/page/year: 28,1444,1972

*** REVIEWS ***

ACGIH TLV-TWA 0.1 mg/m3

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

TLV/BEI,1997

TOXICOLOGY REVIEW

FOREAE Food Research. (Champaign, IL) V.1-25, 1936-60. For publisher

information, see JFDSAZ. Volume(issue)/page/year: 7,313,1942

*** U.S. STANDARDS AND REGULATIONS ***

MSHA STANDARD-air:TWA 0.1 mg/m3

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

3,245,1971

OSHA PEL (Gen Indu):8H TWA 0.1 mg(Te)/m3

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

29,1910.1000,1994

OSHA PEL (Construc):8H TWA 0.1 mg(Te)/m3

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

of Documents, Washington, DC 20402) Volume(issue)/page/year:

OSHA PEL (Shipyard):8H TWA 0.1 mg(Te)/m3

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

29,1915.1000,1993

OSHA PEL (Fed Cont):8H TWA 0.1 mg(Te)/m3

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

of Documents, Washington, DC 20402) Volume(issue)/page/year:

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-AUSTRALIA:TWA 0.1 mg/m3 JAN 1993

OEL-AUSTRIA: MAK 0.1 mg/m3, JAN1999

OEL-BELGIUM:TWA 0.1 mg/m3 JAN 1993

OEL-DENMARK: TWA 0.1 mg/m3, JAN1999

OEL-FINLAND:TWA 0.1 mg/m3;STEL 0.3 mg/m3 JAN 1993

OEL-GERMANY:TWA 0.1 mg/m3 JAN 1993

OEL-THE NETHERLANDS:TWA 0.1 mg/m3 JAN 1993

OEL-THE PHILIPPINES:TWA 0.1 mg/m3 JAN 1993

OEL-SWEDEN:TWA 0.1 mg/m3 JAN 1993

OEL-POLAND: MAC(TWA) 0.01 mg/m3, MAC(STEL) 0.03 mg/m3, JAN1999

OEL-SWITZERLAND:TWA 0.1 mg/m3;STEL 0.5 mg/m3 JAN 1993

OEL-TURKEY:TWA 0.1 mg/m3 JAN 1993

OEL-UNITED KINGDOM:TWA 0.1 mg/m3 JAN 1993

OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV

OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :

NIOSH REL TO TELLURIUM AND COMPOUNDS-air:10H TWA 0.1 mg/m3

REFERENCE :

NIOSH* National Institute for Occupational Safety and Health, U.S. Dept.

of

Health, Education, and Welfare, Reports and Memoranda.

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :

NOHS - National Occupational Hazard Survey (1974)

NOHS Hazard Code - 71197

No. of Facilities: 192 (estimated)

No. of Industries: 5

No. of Occupations: 8

No. of Employees: 472 (estimated)

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - 71197

No. of Facilities: 422 (estimated)

No. of Industries: 10

No. of Occupations: 16

No. of Employees: 12284 (estimated)

No. of Female Employees: 3098 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1999

NIOSH Analytical Method, 1994: Elements by ICP, 7300