Rtecs number : ww2710000 chemical name : Talc (powder), containing no asbestos fibers

TETRAAZACYCLODODECANE

CHEMICAL NAME : 1,4,7,10-Tetraazacyclododecane

CAS REGISTRY NUMBER : 294-90-6

BEILSTEIN REFERENCE NO. : 0606114

REFERENCE : 5-26-11-00023 (Beilstein Handbook Reference)

LAST UPDATED : 199612

DATA ITEMS CITED : 2

MOLECULAR FORMULA : C8-H20-N4

MOLECULAR WEIGHT : 172.32

COMPOUND DESCRIPTOR : Drug

SYNONYMS/TRADE NAMES :

* Cyclen

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intravenous

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 388 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NATWAY Naturwissenschaften. (Springer-Verlag, Heidelberger Platz 3,

D-1000

Berlin 33, Fed. Rep. Ger.) V.1- 1913- Volume(issue)/page/year:

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intravenous

SPECIES OBSERVED : Rodent - mouse

DOSE/DURATION : 435 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique.

(Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France)

V.9- 1974- Volume(issue)/page/year: 19,425,1984

TETRAAZACYCLOTETRADECANE (1,4,8,11-)

CHEMICAL NAME : 1,4,8,11-Tetraazacyclotetradecane

CAS REGISTRY NUMBER : 295-37-4

BEILSTEIN REFERENCE NO. : 0111811

REFERENCE : 5-26-11-00027 (Beilstein Handbook Reference)

LAST UPDATED : 199806

DATA ITEMS CITED : 1

MOLECULAR FORMULA : C10-H24-N4

MOLECULAR WEIGHT : 200.38

COMPOUND DESCRIPTOR : Drug

SYNONYMS/TRADE NAMES :

* Cyclam

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intraperitoneal

SPECIES OBSERVED : Rodent - mouse

DOSE/DURATION : 371 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold

Skin and Appendages - primary irritation (after topical exposure)

REFERENCE :

CMSHAF Chemosphere. (Pergamon Press Inc., Maxwell House, Fairview Park,

Elmsford, NY 10523) V.1- 1972- Volume(issue)/page/year: 17,839,1988

TETRABROMO BISPHENOL A (3,3',5,5'-)

CHEMICAL NAME : Phenol, 4,4'-(1-methylethylidene)bis(2,6-dibromo-

CAS REGISTRY NUMBER : 79-94-7

LAST UPDATED : 199712

DATA ITEMS CITED : 8

MOLECULAR FORMULA : C15-H12-Br4-O2

MOLECULAR WEIGHT : 543.91

COMPOUND DESCRIPTOR : Primary Irritant

SYNONYMS/TRADE NAMES :

* BA 59

* FG 2000

* Fire Guard 2000

* Firemaster BP 4A

* Great Lakes BA-59P

* 4,4'-(1-Methylethylidene)bis(2,6-dibromophenol)

* Saytex RB 100PC

* Tetrabromobisphenol A

* 2,2',6,6'-Tetrabromobisphenol A

* 3,3',5,5'-Tetrabromobisphenol A

* 3,5,3',5'-Tetrabromobisphenol A

* Tetrabromodian

* Tetrabromodiphenylopropane

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test

ROUTE OF EXPOSURE : Administration into the eye

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : 100 mg

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161)

Formerly U.S. Clearinghouse for Scientific & Technical Information.

Volume(issue)/page/year: OTS0525426

** ACUTE TOXICITY DATA **

TYPE OF TEST : LC - Lethal concentration

ROUTE OF EXPOSURE : Inhalation

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : >10920 mg/m3/4H

TOXIC EFFECTS :

Sense Organs and Special Senses (Eye) - effect, not otherwise specified

Behavioral - somnolence (general depressed activity)

Lungs, Thorax, or Respiration - dyspnea

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161)

Formerly U.S. Clearinghouse for Scientific & Technical Information.

Volume(issue)/page/year: OTS0525426

TYPE OF TEST : LC - Lethal concentration

ROUTE OF EXPOSURE : Inhalation

SPECIES OBSERVED : Rodent - mouse

DOSE/DURATION : >500 mg/m3/8H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161)

Formerly U.S. Clearinghouse for Scientific & Technical Information.

Volume(issue)/page/year: OTS0525426

TYPE OF TEST : LD - Lethal dose

ROUTE OF EXPOSURE : Administration onto the skin

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : >3160 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161)

Formerly U.S. Clearinghouse for Scientific & Technical Information.

Volume(issue)/page/year: OTS0525426

TYPE OF TEST : LD - Lethal dose

ROUTE OF EXPOSURE : Inhalation

SPECIES OBSERVED : Rodent - guinea pig

DOSE/DURATION : >500 mg/m3/8H

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161)

Formerly U.S. Clearinghouse for Scientific & Technical Information.

Volume(issue)/page/year: OTS0525426

** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE : Administration onto the skin

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : 100 gm/kg/4W-I

TOXIC EFFECTS :

Kidney, Ureter, Bladder - other changes in urine composition

Endocrine - hyperglycemia

Related to Chronic Data - death

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161)

Formerly U.S. Clearinghouse for Scientific & Technical Information.

Volume(issue)/page/year: OTS0525426

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1999