Rtecs number : ww2710000 chemical name : Talc (powder), containing no asbestos fibers

TUNGSTEN

CHEMICAL NAME : Tungsten

CAS REGISTRY NUMBER : 7440-33-7

LAST UPDATED : 199907

DATA ITEMS CITED : 22

MOLECULAR FORMULA : W

MOLECULAR WEIGHT : 183.85

WISWESSER LINE NOTATION : WO

COMPOUND DESCRIPTOR : Reproductive Effector

Primary Irritant

SYNONYMS/TRADE NAMES :

* Wolfram

*** HEALTH HAZARD DATA ***

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test

ROUTE OF EXPOSURE : Administration onto the skin

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : 500 mg/24H

REACTION SEVERITY : Mild

REFERENCE :

28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,"

Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho

Prumyclu

Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,19,1972

TYPE OF TEST : Standard Draize test

ROUTE OF EXPOSURE : Administration into the eye

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : 500 mg/24H

REACTION SEVERITY : Mild

REFERENCE :

28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku,"

Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho

Prumyclu

Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,19,1972

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intraperitoneal

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 5 gm/kg

TOXIC EFFECTS :

Vascular - regional or general arteriolar or venous dilation

Liver - other changes

Blood - other changes

REFERENCE :

INMEAF Industrial Medicine. (Chicago, IL) V.1-18, 1932-49. For

publisher

information, see IOHSA5. Volume(issue)/page/year: 15,482,1946

** REPRODUCTIVE DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE : 1210 ug/kg

SEX/DURATION : female 35 week(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - post-implantation mortality (e.g. dead and/or

resorbed implants per total number of implants)

Reproductive - Specific Developmental Abnormalities - musculoskeletal

system

GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O

Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936-

Volume(issue)/page/year: 42(8),30,1977

TYPE OF TEST : TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE : 1160 ug/kg

SEX/DURATION : female 30 week(s) pre-mating

female 1-20 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - musculoskeletal

system

REFERENCE :

see

1939- Volume(issue)/page/year: 41,620,1978

*** U.S. STANDARDS AND REGULATIONS ***

MSHA STANDARD-air:TWA 1 mg/m3 (soluble)

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

3,272,1971

MSHA STANDARD:air-TWA 5 mg/m3 (insoluble)

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

3,272,1971

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-RUSSIA:STEL 2 mg/m3 JAN 1993

OEL-SWEDEN:TWA 5 mg/m3 JAN 1993

OEL-DENMARK: TWA 5 mg/m3, JAN1999

OEL-UNITED KINGDOM:TWA 5 mg/m3;STEL 10 mg/m3 JAN 1993

OEL-POLAND: MAC(TWA) fume and dust 5 mg/m3, JAN1999

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :

NIOSH REL TO TUNGSTEN, insoluble-air:TWA 5 mg(W)/m3;STEL 10 mg/m3

REFERENCE :

NIOSH* National Institute for Occupational Safety and Health, U.S. Dept.

of

Health, Education, and Welfare, Reports and Memoranda.

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :

NIOSH REL TO TUNGSTEN, soluble-air:10H TWA 1 mg(W)/m3;STEL 3 mg/m3

REFERENCE :

NIOSH* National Institute for Occupational Safety and Health, U.S. Dept.

of

Health, Education, and Welfare, Reports and Memoranda.

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :

NOHS - National Occupational Hazard Survey (1974)

NOHS Hazard Code - 74980

No. of Facilities: 530 (estimated)

No. of Industries: 20

No. of Occupations: 24

No. of Employees: 4735 (estimated)

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - X5928

No. of Facilities: 53 (estimated)

No. of Industries: 4

No. of Occupations: 11

No. of Employees: 3907 (estimated)

No. of Female Employees: 1258 (estimated)

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - X7685

No. of Facilities: 174 (estimated)

No. of Industries: 5

No. of Occupations: 15

No. of Employees: 4822 (estimated)

No. of Female Employees: 3021 (estimated)

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - 74980

No. of Facilities: 1623 (estimated)

No. of Industries: 52

No. of Occupations: 43

No. of Employees: 38323 (estimated)

No. of Female Employees: 3591 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1999

NIOSH Analytical Method, 1994: Tungsten (soluble and insoluble), 7074