Rtecs number : ww2710000 chemical name : Talc (powder), containing no asbestos fibers

TRIZMA BASE

CHEMICAL NAME : 1,3-Propanediol, 2-amino-2-(hydroxymethyl)-

CAS REGISTRY NUMBER : 77-86-1

OTHER CAS REGISTRY NOS. : 25149-07-9

108195-86-4

LAST UPDATED : 199706

DATA ITEMS CITED : 7

MOLECULAR FORMULA : C4-H11-N-O3

MOLECULAR WEIGHT : 121.16

WISWESSER LINE NOTATION : Q1XZ1Q1Q

COMPOUND DESCRIPTOR : Drug

SYNONYMS/TRADE NAMES :

* Addex-tham

* 2-Amino-2-(hydroxymethyl)propane-1,3-diol

* 2-Amino-2-(hydroxymethyl)-1,3-propanediol

* 2-Amino-2-methylol-1,3-propanediol

* Aminotrimethylolmethane

* Aminotris(hydroxymethyl)methane

* Methylamine, 1,1,1-tris(hydroxymethyl)-

* Pehanorm

* Talatrol

* THAM-E

* Trimethylolaminomethane

* Tris (buffering agent)

* Trisamine

* Tris-amino

* Trisaminol

* Tris buffer

* Tris-hydroxymethyl-aminomethan

* Tris-hydroxymethylaminomethane

* Tris(hydroxymethyl)methanamine

* Tris(hydroxymethyl)methylamine

* Trispuffer

* Tris-steril

* Trometamol

* Trometamole

* Tromethamine

* Tromethane

* Tromethanmin

* Tutofusin tris

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 5900 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale

Farmaceutica,

Via Ausonio 12, 20123 Milan, Italy) V.33- 1894-

Volume(issue)/page/year:

110,653,1971

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intravenous

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 1800 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo,

Japan) Volume(issue)/page/year: -,419,1990

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intravenous

SPECIES OBSERVED : Rodent - mouse

DOSE/DURATION : 1210 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.)

V.1-41,

1958-82. For publisher information, see BBIADT. Volume(issue)/page/year:

TYPE OF TEST : LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE : Oral

SPECIES OBSERVED : Rodent - rabbit

DOSE/DURATION : 1 gm/kg

TOXIC EFFECTS :

Behavioral - somnolence (general depressed activity)

Behavioral - muscle weakness

Behavioral - coma

REFERENCE :

JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA)

V.18-31, 1936-49. For publisher information, see AEHLAU.

Volume(issue)/page/year: 22,315,1940

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :

NOHS - National Occupational Hazard Survey (1974)

NOHS Hazard Code - 81165

No. of Facilities: 850 (estimated)

No. of Industries: 4

No. of Occupations: 6

No. of Employees: 7274 (estimated)

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - 81165

No. of Facilities: 2296 (estimated)

No. of Industries: 9

No. of Occupations: 22

No. of Employees: 40897 (estimated)

No. of Female Employees: 30773 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

TROPAEOLIN O

CHEMICAL NAME : Benzenesulfonic acid,

4-((2,4-dihydroxyphenyl)azo)-,

monosodium salt

CAS REGISTRY NUMBER : 547-57-9

LAST UPDATED : 199701

DATA ITEMS CITED : 3

SYNONYMS/TRADE NAMES :

* Acid Leather Yellow PGW

* Acid Orange 6

* Acid Phosphine G New

* ACME Yellow Acid Yellow RS

* Cetil Chromine Yellow GR

* Chrysoine

* Chrysoine Extra

* Chrysoine Extra Pure A

* Chrysoine N

* Chrysoine S

* Chrysoine S Extra Pure

* Chrysoin G

* Chrysoin S

* Chrysoin S Specially Pure

* Chrysonine S

* C.I. 14270

* C.I. Acid Orange 6

* C.I. Acid Orange 6, monosodium salt

* C.I. Food Yellow 8

* Curol Orange G

* C Yellow 12

* Dermina Yellow G

* E 103

* E 103 (dye)

* Eurocert Chrysoine S

* Gold Yellow

* Hispacid Yellow CG

* Monosodium 4-((2,4-dihydroxyphenyl)azo)benzenesulfonate

* Naphthazine Yellow RP

* Neklacid Yellow G

* Orange Acid G

* Resorcine Yellow

* Resorcine Yellow O Extra

* Resorcinol Yellow

* Resorcinol Yellow A

* Resorcin Yellow

* Sodium azoresorcinolsulfanilate

* Tertracid Yellow TRO

* Tropaeoline

* Tropaeolin O

* Tropaeolin R

* Tropeolin O

* Yellow T

*** HEALTH HAZARD DATA ***

** ACUTE TOXICITY DATA **

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intraperitoneal

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : >1 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353

Vineuil,

France) V.1- 1943- Volume(issue)/page/year: 15,402,1957

TYPE OF TEST : LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE : Intravenous

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : >1 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

APFRAD Annales Pharmaceutiques Francaises. (SPPIF, B.P.22, F-41353

Vineuil,

France) V.1- 1943- Volume(issue)/page/year: 15,402,1957

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY