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Curriculum Vitae Ming-Daw Tsai, Ph. D


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BCEIA), Beijing, November 25-28, 2009. (Keynote speaker)

  • “Protein-phosphoprotein interactions of phosphothreonine-specific FHA domains”. Nankai University, Tianjin, Nov. 27, 2009. (Host: George Wang)

  • “An Enzymologist's Approach to Histone Demethylases”. The 5th Chromosome Biology Mini-Symposium. Institute of Molecular Biology, Academia Sinica, Taiwan, Dec. 2-3, 2009.

  • “A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase Cascade”. Department of Structural Biology, University of Pittsburgh. December 7, 2009.

  • “Structure and Mechanism of Mutagenic DNA Polymerase X”. Taiwan Enzyme Mechanism Conference, Academia Sinica, Taipei, Taiwan, Dec 15, 2009.

  • “Protein-Protein Interactions as Potential Drug Targets”. 7th International Symposium for Chinese Medicinal Chemists (ISCMC-2010), Kaoshiung Medical University, Feb. 1-5, 2010.

  • “Counting the Phosphates of a Phosphorylation Site Cluster”. 2010 Disease Biomarker and TPS International Conference, Chang-Gung, Taipei, April 23-24, 2010.

  • “A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase Cascade”. ETH, Zurich, Switzerland, May 7, 2010.

  • “Mechanism of High-Fidelity and Mutagenic DNA Polymerases”. International Conference on Evolving DNA Polymerases: Chemistry meets Biology, Monte Verità, Switzerland, May 9-14, 2010.

  • “Mechanism and specificity of Protein-phosphoprotein interactions”. 10th Taiwan International Symposium on Statistical Physics: Critical Phenomena and Complex Biological Systems, Institute of Physics of Academia Sinica, July 27-31, 2010.

  • “A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase Cascade”. UCSD-Taiwan Symposium, San Diego, September 16-17, 2010.

  • “A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase Cascade”. National Institutes of Health, Washington DC, October 22, 2010.

  • “A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase Cascade”. Dept of Pharmacology, Johns Hopkins University, October 24, 2010.

  • “Protein-(phospho)protein interactions as potential drug targets”. National Taiwan University College of Pharmacy, Nov. 8, 2010.

  • “蛋白質的奧密”. National Chiao-Tung University, December 10, 2010.

  • “Structure and Mechanism of Mutagenic DNA Polymerase X”. Pacifichem of American Chemical Society, Honolulu, December 16-20, 2010.

  • “Structural and Mechanistic Bases for the G:G Specificity of ASFV DNA Polymerase X”. 22nd Enzyme Mechanisms Conference, Loews Don CeSar Beach Resort, St. Pete Beach, Florida, January 3-5, 2011.

  • “Structure and Mechanism of a Viral DNA Polymerase with G:G Specificity”. Asian Biophysical Society Meeting, New Dehli, Jan 30 – Feb. 1, 2011. (Plenary)

  • “Structure and Mechanism of a Viral DNA Polymerase with G:G Specificity”, 76th Israel Chemical Society Meeting, Tel Aviv, Feb 9-10, 2011.

  • “Structure and function of FHA domains in DNA damage and cancer signaling”. National Chung-Hsing University, April 15, 2011.

  • “Influenza virus inhibitors that disrupt the nucleoprotein trimer”. Academia Sinica – Johnson & Johnson Bilateral Symposium on Infectious Diseases, April 27-28, 2011.

  • “FHA, a signaling domain with diverse specificities and functions”. FAOBMB Micro Symposium on "Advances in biochemistry and molecular biology for biomedical applications". Academia Sinica, Taipei, May 6, 2011.

  • “Structure and function of FHA domains in DNA damage and cancer signaling”. 100年度國家衛生研究院生物醫學學術研討會, Chu-Nan, August 15-16, 2011.

  • “Influenza virus inhibitors that disrupt the nucleoprotein trimer”. National Research Institute of Chinese Medicine, Taipei, Sept 21, 2011.

  • “FHA, a signaling domain with diverse specificities and functions”. FAOBMB Conference, Singapore, October 5-7, 2011.

  • “How some error prone DNA polymerases overcome Watson-Crick base pairing”. The 17th International Biophysics Congress (IUPAB), Beijing, Oct 31 – Nov. 3, 2011.

  • “Counting Phosphates”. 2011 International Conference on Functional Proteomics: Advances in Post-translational Modification. Academia Sinica, Taipei, November 14-15, 2011.

  • “How some error prone DNA polymerases overcome Watson-Crick base pairing”. 2nd Taiwan Enzyme Mechanism Conference, Taichung, December 15-16, 2011. (Plenary)

  • “A Phosphate-counting Mechanism for Sequential Activation of a Checkpoint Kinase”. UC Davis, Sacramento, CA, Feb 17, 2012.

  • “Studies of proteins involved in cell cycle progression that are closely related with cancer and DNA damage”. KMU Biomedical Symposium, March 21-22, 2012.

  • “Mechanism of Rad53 kinase activation in vivo - counting the phosphates by FHA domains”. Department of Chemistry, UC Berkeley, Berkeley, CA, March 23, 2012.

  • “How many phosphorylation sites can a protein have, and what are the functions of multi-site phosphorylations?” Taiwan Proteomics Society meeting, May 31 – June 1, 2012, KMU.

  • “How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53”. 8th International Symposium on Biocatalysis and Biotechnology, Sonoma Wine Country, CA, Oct 28-31, 2012.

  • “How a phosphorylation cluster regulates the activation and function of yeast checkpoint kinase Rad53”. FAOBMB Congress, Bangkok, Thailand, November 25-29, 2012.

  • “Enzyme mechanisms from in vitro to in vivo”. AS-CAS Bilateral Conference, Beijing, Dec 3-4, 2012.

  • “The entangled triangular relationship between structure, function, and mechanism of proteins”. 21st Cell and Molecular Biology Frontier Science Symposium, Ken-Ding Park, 1/30 to 2/1, 2013. (Plenary Lecture)

  • “Protein-phosphoprotein complexes in DNA damage and cancer signaling”. RIKEN-Academia Sinica Joint Conference, Taipei, March 2, 2013.

  • “The entangled triangular relationship between structure, function, and mechanism of proteins”. National Central University, April 25, 2013.

  • “Functions of phosphorylation site clusters and multiple phosphorylations”. 2013 Taiwan Proteomics Society International Conference: Recent Advances in Translational Medicine, Taipei Medical University, May 24-25, 2013.

  • “Protein-phosphoprotein complexes in DNA damage and cancer signaling”. 12th HUPO World Congress, Yokohama, Japan, September 14-18, 2013.

  • “Protein-phosphoprotein complexes in DNA damage and cancer signaling”. The 13th KIAS Conference on Protein Structure and Function, Seoul, Korea, September 26-28, 2013.

  • “Nucleoprotein as a target for influenza virus inhibitors”. Yonsei University, Seoul, Korea, September 30, 2013. (Host: Young-Ki Paik)

  • “How phosphothreonine recognition by FHA domains control diverse biological functions”. University of Alberta, Alberta, Canada, October 25, 2013. (Host: Todd Lowary) [Distinguished Asian Visiting Speaker]

  • “How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation”. Fourth Conference of the Asia Pacific Protein Association (APPA2014), Jeju Island, Korea, May 17-20, 2014. [Plenary lecture]

  • “Chemical Specificity in Biology”. 103年度生命科學組第29屆新科院士演講. Academia Sinica, June 27, 2014.

  • “Structural approach to tumor suppressors and cancer signaling”. 2014 International Symposium for Recent Advances in Cancer (2014 ISRAC), Taipei Medical University, June 28, 2014.

  • “Mechanisms of phosphothreonine signaling and kinase activation”. Department of Chemistry and Biochemistry, The Ohio State University, Columbus, Ohio, October 9, 2014.

  • “How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation”. Korea-Taiwan Biophysical Conference, Daeyue, Korea, Nov 21-22, 2014.

  • “Mechanisms of phosphothreonine signaling and checkpoint kinase activation”. 13th International Symposium for Chinese Organic Chemists (ISCOC-13), Xiamen, December 19-22, 2014. [Plenary Lecture]

  • “Mechanisms of phosphothreonine signaling and checkpoint kinase activation”. 24th Enzyme Mechanisms Conference, Galvaston, Texas, January 4-8, 2015.

  • “How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation”. College of Pharmacy, University of Texas at Austin, Jan 9, 2015.

  • “Unique mechanisms of phosphothreonine signaling in DNA damage response and cancer”. 2015 Scripps meeting “Frontier in Biomedical Sciences”. Feb 14-16, 2015.

  • “Chemical Specificity in Biology”. 生物醫學聯合學術年會, March 21, 2015 (Keynote Lecture)

  • “Solution NMR studies of the structure and mechanism of DNA polymerases”. 6th Asia-Pacific NMR Symposium, at The Hong Kong University of Science and Technology (HKUST) August 13-16, 2015.

  • “How some low-fidelity DNA polymerases choose non-Watson-Crick from Watson-Crick incorporation”. 7th Beilstein ESCEC Symposium, Rudesheim, Germany. September 14 - 18, 2015.

  • “Use of site specifically phosphorylated proteins to examine the mechanism of autophosphorylation of Rad53 kinase”. 2015 RIKEN-Academia Sinica Joint Conference on Chemical Biology, Academia Sinica, Taipei, Oct 15-16.

  • “TIFA, immunity, and cancer”. Chang-Gung University, Taipei. Oct 30, 2015.

  • “How a low-fidelity DNA polymerase chooses non-Watson-Crick from Watson-Crick incorporation”. Pacifichem 2015, December 15-20, 2015.




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