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University Medical School of Debrecen Annual Report 1998–99 Edited by: Pál Gergely and Péter Kovács


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Dániel Bereczki Department of Neurology

Sándor Damjanovich Department of Biophysics and Cell Biology

István Degrell Department of Psychiatry

Zsigmond Fehér Department of Human Genetics

István Fekete Department of Neurology

László Fésüs Department of Biochemistry and Molecular Biology

Lajos Gergely Department of Microbiology

Ms Irén Horkay Department of Dermatology and Venerology

László Kovács Department of Physiology

Péter Kovács Department of Pharmacology

Géza Lukács 1st Dept. of Surgery

János Matkó Department of Biophysics and Cell Biology

Ferenc Mechler Department of Neurology

László Módis Department of Anatomy, Histology and Embryology

Péter Molnár Department of Behavioural Sciences

László Nagy Department of Biochemistry and Molecular Biology

György Pfliegler 2nd Dept. of Internal Medicine

Imre Semsei 3rd Dept. of Internal Medicine

Zoltán Szekanecz 3rd Dept. of Internal Medicine

Ferenc D.Tóth Department of Microbiology

Lajos Trón Positron Emission Tomograph Centre

Ferenc Wórum 1st Dept. of Internal Medicine

Imre Zsolnai-Nagy Department of Gerontology

Széchenyi Professorial Fellowships awarded in 1999 for 2000-2003

Attila Bánfalvi Department of Behavioural Sciences

Zoltán Boda 2nd Dept. of Internal Medicine

György Csécsei Department of Neurosurgery

Balázs Dezső Department of Pathology

István Furka Department of Experimental Surgery

Jolán Hársfalvi Dept. of Clinical Biochemistry and Molecular Pathology

Sándor Imre Dept. of Pathophysiology

István Juhász Department of Dermatology and Venerology

János Kappelmayer Dept. of Clinical Biochemistry and Molecular Pathology

Gusztáv Keszthelyi Department of Stomatology

Csongor Kiss Department of Pediatrics

Zoltán Krasznai Department of Biophysics and Cell Biology

István Lőrincz 1st Dept. of Internal Medicine

Mátyás Sipiczki Department of Human Genetics

István Sziklai Department of Otolaryngology




4.3. Foreign Scholarships

Department of Anatomy

Ákos Kulik Department of Morphological Brain Science, Faculty of Medicine, Kyoto University (Kyoto, Japan) 17 March 1997-13 March 1999
Fellowship of the Japan Society for the Promotion of Science

Ms Erika Polgár University of Glasgow, Institute of Biomedical & Life Sciences, Division of Neuroscience & Biomedical Systems, Laboratory of Human Anatomy (Glasgow, Scotland) 1 May 1999-1 May 2000
Wellcome Trust Fellowship

Péter Szűcs MRC Anatomical Neuropharmacology Unit (Oxford, United Kingdom) 1 October 1998 -1 October 1999

Ervin Wolf School of Biological Sciences, University of Bristol, UK
15 July 1999-31 October 1999
Wellcome Trust Fellowship

Department of Biochemistry and Molecular Biology

János Aradi State University of New York at Buffalo, School of Pharmacy, Dept. of Medical Chemistry (Buffalo, USA) 11 June 1998-18 Sept. 1998

Péter Boross NCI-Frederick Cancer Research & Development Center (Frederick, USA) 26 June-5 September 1999

András Kovács University of Dundee (U.K., Scotland) 1 September -30 November, 1998

László Nagy The Salk Institute for Biological Studies, Gene Expression Lab., (La Jolla, CA, USA) 21 February 1996-30 June 1999

Zoltán Nemes NIH, National Institute of Arthrosis, Muscoskeletal and Skin Diseases (Bethesda, MD., USA) 11 November 1996-25 May 1999

Ms Éva Szegezdi University of Nottingham (U.K.) 1-30 November 1998

Ms Zsuzsa Szondy Institute Pasteur, Unite d'Oncologie Virale, Departement side et Retrovirus (Paris, France) 12 October 1998-21 November 1998

József Tőzsér NCI-Frederick Cancer Research & Development Center (Frederick, USA) 26 June-5 September 1999

Department of Biophysics and Cell Biology

Zsolt Bacsó Barbara Ann Karmanos Cancer Institute, Wayne State School of Medicine (Detroit, Michigan, USA) 1997-1999. Barbara Ann Karmanos Cancer Institute fellowship

Andrea Bodnár University of Regensburg, Department of Clinical Chemistry and Laboratory Medicine, 14 October 1998-11 December 1998 and 1 June 1999-31 July 1999.
German Academic Exchange Service (DAAD)

Attila Jenei Dept. of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 1998-present, European Molecular Biology Organization Long Term Postdoctoral Fellowship

György Panyi Dept. of Physiology, University of Pennsylvania (Philadelphia, USA) February 1999-April 1999, US Hungarian Joint Project

Péter Salga Dept. of Molecular Biology, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, 1 October 1998-22 December 1998, TEMPUS scholarship

György Vámosi Max Planck Institute for Biophysical Chemistry, Göttingen, Germany, November 1998-December 1998, German Academic Exchange Service (DAAD)

Department of Hygiene and Epidemiology

Zsuzsa Ádám Medical School of Leiden, 1 August 1998-30 Oct. 1998, TEMPUS project

Ms Margit Balázs 2nd Dept. of Pathology Gifu University School of Medicine, 5 weeks. Hungarian-Japanese Intergovernmental Cooperation in S T

Ms Helga Bárdos London School of Hygiene and Tropical Medicine, London, UK
1 year, World Bank loan to the implementation of School of Publich Health in Hungary

Ms Zsuzsa Pocsai London School of Hygiene and Tropical Medicine, London, UK
1 year, World Bank loan to the implementation of School of Publich Health in Hungary

Zsolt Petkó Erasmus University of Rotterdam, 1 Aug. 1998-31 July 1999, World Bank loan to the implementation of School of Publich Health in Hungary

László Tóth The University of Iowa, Center for International Rural and Environmental Health, Iowa City, USA, 18 July 1999-17 December 1999, Fogarty International Training Program in Environmental and Occupational Health (CIREH)

Department of Medical Chemistry

Ms Andrea Murányi Muscle Biology Group (1998-2000)
Supported by University of Arizona

Balázs Szöőr University of Oxford, Department of Zoology, Oxford, UK, 1 Febr. 1998-30 Jan. 1999
Supported by University of Oxford

László Virág INOTEK Inc. Beverly, MA, USA
Fellowship provided by: INOTEK Inc.

Department of Microbiology

Attila Juhász Karolinska Institutet, Stockholm, Sweden, 4 September 1998-3 December 1998
Tempus 12071-97

Zoltán Beck Karolinska Institutet, Stockholm, Sweden, 1 September 1998-24 November 1998
Tempus 12071-97

Department of Pathophysiology

László Virág Div. of Critical Care, Children’s Hospital Medical Centre, Cincinnati, Ohio, USA. 20 January 1997-20 January 1999

Department of Pharmacology

Ms Anikó Ujfalusi Laboratory of Matrix Pathobiology, Pacific Biomedical Research Center, University of Hawaii, Honolulu, USA, Nov. 1997-Dec. 1998

Attila Iglói DAAD-MÖB, Freie Universität Berlin, Fachbereich Pharmazie, Institut für Pharmazie II, Pharmakologie und Toxikologie, Berlin, Deutschland, July 1999-September 1999

Department of Physiology

László Csernoch Dept. of Physiology, Claude Bernard University of Lyon I, Lyion, France
1 June 1999-30 June 1999, financed by the Claude Bernard University

Zoltán Papp Department of Physiology, Free University, Amsterdam, The Netherlands, 1 Jan. 1998-31 Dec. 1999
financed by the OTKA-NWO (grant No 97/99)

Sándor Sárközi Department of Applied Physiology, University of Ulm, Ulm, Germany, 4 November 1998-28 February 1999
financed by the DFG

István Sipos Department of Applied Physiology, University of Ulm, Ulm, Germany, 16 October 1996-15 October 1998
financed by the OMFB-DFG (grant No. D-105) and the European Community (ERB 4061 PL 95-0522 Network Program)

Gyula Szigeti Department of Pharmacology and Cell Biophysics, University of Cincinnati, Cincinnati, USA, 1 July 1998-30 June 2000
financed by an NIH research grant

Department of Gerontology

Ferenc Horváth Darhmouth-Hitchcook Medical School, Dept. of Radiology, Hanover, NH. USA, 3 months
financed by the inviting institute

School of Public Health

László Kardos London School of Hygiene and Tropical Medicine, London, Great Britain, September 1998-September 1999

Department of Cardiac Surgery

Endre Jagamos Hjartcentrum Thorax, Umeä, 1 Sept. 1998-31 Aug. 1999

Zsolt Nagy Killingeck Hospital, Leeds, England, 1 September 1998-31 December 1998

Zoltán Szabó Dept.of Cardiothoracic Surgery, University Hospital, Linköping, Sweden, 1 September 1998-30 June 1999

István Szentkirályi Hjartcentrum Thorax, Umeä, 6 May 1999-31 Aug. 1999

Ms Éva Tamás Dept. of. Cardiothoracic Surgery, University Hospital, Linköping, Sweden, 1 September 1998-31 Aug. 1999

Department of Dermatology and Venerology

Norbert Wikonkál Department of Therapeutic Radiology, Yale Univ. School of Medicine, New Haven, CT, USA, 1 December 1996-
Granted by Douglas E. Brash, Ph.D. Associate Professor

Imre Szabó, Temple University, Office of International Services, 1 December 1998-31 December 2000
Granted by Thomas J. Rogers

1st Department of Internal Medicine

József Balla University of Minnesota, Beth Israel Medical Center, Harvard Medical School, 1 March 1999-30 May 1999
Organized by University of Minnesota

2nd Department of Internal Medicine

István Tornai Laboratory for Thrombosis Research, IRC, Catholic University of Leuven, Campus Kortrijk, Kortrijk, Belgium, Flemish-Hungarian International Scientific and Technological Cooperation B13/96.

3rd Department of Internal Medicine

Zsolt Barta University Kentucky, Lexington, Kentucky, USA, 1 April-31 May 1999

Ms Edit Gyimesi Charlottesville, USA, 1 September 1998-1 September 2000-05-17

Department of Neurology

Dániel Bereczki Tohoku Gakuin University, Japan, Sendai, 6 August 1997-1 April 1998

Levente Kerényi John Hopkins Hospital, Baltimore, USA, 9 November 1997 -

Zoltán Káposzta Academic Neuroscience Centre, London, UK, 1 March 1998 -

László Oláh Max-Planck-Institut für Neurologische Forschung, Köln, Deutschland, 1 April 1998-

Department of Neurosurgery

Álmos Klekner University of Köln, Neurosurgical Department, 1 October 1998-31 July 1999, DAAD

Department of Ophthalmology

László Módis Westfalische Wilhelms Universität, Münster, Klinik und Poliklinik für Augenheilkunde
Eötvös Grant of the Hungarian State

Attila Bíró Ophthalmology Clinic of the University of Genova

Department of Otolaryngology

Attila Szűcs Northwestern University, Evanston, Illinios, 8 March 1999-31 May, 1999

Department of Orthopaedic Surgery

Zoltán Csernátonyi Bourse d'Etudes de Haut Niveau du Gouvernement Français Département de Chirurgie Orthopédique et de Traumatologie, Hôpital Lariboisière, Paris, April-June 1999

Department of Radiology

Éva Simon Department of Radiology, Tenon Hospital Paris, 1-30 June 1999
Financed by a grant by the French Government

1st Department of Surgery

Ms Krisztina Litauszky Linköping, Sweden, 1-30 September 1998

Department of Urology

Miklós Szűcs Allgemeines Krankenhaus Wien-University Hospital, March-April 1999
American Austrian Foundation

László Lőrincz Charitas Krankenhaus Bad-Merghentheim, January-May 1998
Deutsche Gessellschaft für Urologie (Europa Komission)




5. Staff Changes

5.1. Retired

Ms Róza Gombi M.D., Ph.D. Associate Professor Dept. of Neurosurgery

Ms Ágota Schnitzler M.D., Ph.D. Assistant Professor Dept. of Ophthalmology

János Rigó M.D., Ph.D. Full Professor Dept. of Orthopaedic
Surgery



5.2. Deceased

Imre Jakabfi retired Full Professor Dept. of Otolaryngology

Béla Kövér retired Full Professor Dept. of Pediatrics




6. Scientific Meetings Organized by Staff Members

Department of Anatomy, Histology and Embriology

Heikki J. Helminen (Dept. of Anatomy, University of Kuopio): A few approaches to solve the functional properties of articular cartilage and the pathogenesis of osteoarthritis, 16 October, 1998.

Árpád Szállási (National Cancer Institute Bethesda, Maryland) Vanilloid-sensitive neurons: from capsaicin through cloning to clinical treatment. 19 October, 1998.

1st Conference on Neuroscience organised by the Association of Debrecen Universities "Theoretical and Clinical Aspects of Neuroscience in north-eastern Hungary and the neighbouring countries". 6-7 November, 1998.

Mika Hyttinen (Dept. of Anatomy, University of Kuopio) Knocking out of type II and XI collagens: microscopical phenotype of articular cartilage and subchondral bone. 10 December, 1998.

Oleg Shupliakov (Dept. of Neurosci., Karolinska Institute, Stockholm) Molecular mechanisms controlling synaptic vesicle endocytosis. 15 February, 1999.



Department of Biophysics and Cell Biology

Future Trends in Quantitative Cytology for Clinical and Research Applications. 13-16 May, 1999, Hortobágy-Epona, Hungary. ISAC (An international conference sponsored by the International Society for Analytical Cytology, 150 participants).



Department of Clinical Biochemistry and Molecular Pathology

20 years in the service of clinical pathology, 11 December 1998

László Muszbek: Symposium: Novel Aspect of Hemostasis and Thrombosis IFCC-Worldlab '99, 6-11 June 1999

Department of Pharmacology

14th Conference of the Hungarian Society for Chemotherapy, Hajdúszoboszló, 2-4 June 1999.

2nd European Congress of Pharmacology, Budapest, 3-7 July 1999

Research Trends in the Therapy of Autoimmune Diseases: Blockade of MHC or TNFalpha, Induction of Regulator T-cells. Scientific Session of the Immunopharmacology Section of the Hungarian Society for Experimental and Clinical Pharmacology and of the Working Committee on Pharmacology and Pharmacy of the Debrecen Regional Organization of the Hungarian Academy of Sciences, Debrecen, 2 December 1998

Scientific Session of the University Medical School of Debrecen: Review of Research in the Department of Pharmacology, 25 January 1999

Positron Emission Tomograph Centre

Scientific meeting on Positron Emission Tomography, 22 February 1999



School of Public Health

EMIKK 9th National Conference on Quality Control Systems, 11-12 December 1998, Hajdúszoboszló

OMFB Technology Development Programme: Meeting of Work Group of Health and Life Sciences, 25 March, 1999 School of Public Health, Debrecen

EMIKK 10th National Conference: Education as the First Step of Quality Improvement, 16-17 April 1999. Hajdúszoboszló



Department of Cardiac Surgery

A presentation on the effects of sport on health. 27 November 1998

Jubilee Scientific Meeting, 19 December 1998.

Department of Dermatology and Venerology

Annual Meeting of Hungarian Dermatological Society 15-17 October 1998, Lillafüred



Department of Heart and Lung Diseases

4th Debrecen Symposium on Cardiology, 4-6 March 1999.



1st Department of Internal Medicine

5th Nephrological Days in Debrecen, 19-22 May, 1999

1st Congress of Hungarian Clinical Pharmacologists, 21-23 January 1999, Debrecen

Borderline questions in endocrinology, 10 September 1998.

Arrhythmia and Pacemaker Days in Debrecen, 10-12 September 1998.

3rd Debrecen Thyroid International, 27-29 May, 1999



2nd Department of Internal Medicine

Actual problems of Oncohaematological Diagnosis and Therapy, 24 November 1998, Debrecen

Conference of the Hungarian League Against Cancer on the occasion of the 7th Campaign Day Against Cancer
What are the objectives of the "National programmes of the fight against cancer" in the developed world? 29 April 1999, Debrecen

3rd Department of Internal Medicine

Annual Congress of the Hungarian Society of Rheumatologists



Department of Obstetrics and Gynecology

Zoltán Tóth: Ultrasound in Obstetrics and Gynaecology. Postgraduate course
9-13 November 1998

István Batár: International Postgraduate Training Courses in reproductive health/family planning for service providers from countries with economies in transition (UNFPA), 21 September-23 October 1998 and 12 April-14 May 1999

László Lampé 4th International Symposium on the Pregnant Uterus, 16-18 October 1998

Antal Borsos: Scientific Meeting Series of the Department of Obstetrics and Gynaecology
Intraoperative Complications in Obstetrics and Gynaecology. 4 December, 1998
Emergency cases in obstetrics and gynaecology 12 March 1999

Ádám Balogh: Menopause and Osteoporosis. Postgraduate course, 19-20 March 1999

Péter Csiszár: Gynaecologic Endoscopy. Postgraduate Teaching Course, 2-6 March 1998

Péter Csiszár: Regional Refreshing Course for Specialists in Obstetrics and Gynaecology, 8-12 March 1999

Antal Borsos: 2nd National Congress of Hungarian Society of Assisted Reproduction, 18-19 June 1999

Department of Ophthalmology

Scientific Meeting in Allergology, Organized with Dept. of Dermatology of the Univ. Med. School of Debrecen


Alcon Company, September, 1998

New Aspects of Glaucoma Therapy, Allergan Company, October, 1998

Scientific Session of the Children's Ophthalmological Care Foundation of Hajdú-Bihar County, the Hungarian Association of Paediatric Ophthalmologists and Strabologists and the Local Committee of the Hungarian Academy of Science, November 1998

Course on Ophthalmology of the Univ. Med. School of Debrecen, Alcon Company, April 1999

Plenary Session of the Hungarian Society of Ophthalmology: Complications of Diabetes Mellitus, Crossroads in Medicine, 6th International Congress, July 1999

Department of Orthopaedic Surgery

Scientific Meeting, DAB, Debrecen, 23 November 1998



Department of Pediatrics

"Pediatric evening held in the Clinic” - Introduction of the Borsod-Abaúj-Zemplén county Childern's Health Center


25 September 1998, Debrecen

"Pediatric evening held in the Clinic” – Hypertension in childhoold


30 October 1998, Debrecen

"Pediatric evening held in the Clinic” – Contemporary diagnosis and therapy of asthma in children


27 November 1998, Debrecen,

"Pediatric evening held in the Clinic” – Introduction of the Paediatric Department of "Gyula Kenézy" County Hospital


26 February 1999, Debrecen

"Pediatric evening held in the Clinic” - Advances in paediatric dermatology


26 March 1999, Debrecen

"Pediatric evening held in the Clinic” - Growth retardation


23 April 1999, Debrecen

Postgraduate Course in Neonatal Intensive Care


31 May-2 June 1999, Debrecen

Postgradual courses on Tuesdays



Department of Radiology

Gyula Elischer Commemoriation Assembly, Debrecen, 5 March, 1999

The place of the digital radiology in 1999. Debrecen, 30 April 1999

Department of Stomatology

The Hungarian Dental Associations North East Regional Scientific Session, 4 December 1998, Nyíregyháza

Scientific session organized by DAB Stomatological Committee, North East Regional Scientific part of Hungarian Dental Association and L&L Kft, 30 April 1999, Debrecen

Endodontical Days in Debrecen: postgraduate course held by Prof. Martin Trope and Prof. Gunnar Bergenholtz, 20-21 May 1999



1st Department of Surgery

8th Congress of the Coloproctology Section of the Hungarian Society of Surgery, 25-27 March 1998, Hortobágy, Hotel Epona



2nd Department of Surgery

Annual Scientific Meeting of the 2nd Dept. of Surgery, 22 December 1998

Scientific Forum of the Hungarian Young Surgeons, 20 March 1999

Department of Traumatology

Symposium on Pediatric Surgery, Hortobágy-Epona, 16-18 May 1998



Department of Urology

1st Meeting of Young Urologists in English, 1998

25th Anniversary Meeting of the Dept. of Urology, 1999




7. List of Publications

7.1. Departments of Basic Medicine

Department of Anatomy, Histology and Embryology

1. Matesz, C., Schmidt, I., Szabó, L., Birinyi, A., Székely G.: Organization of the motor centres for the innervation of different muscles of the tongue: a neuromorphological study in the frog.


Eur. J. Morphol. 37, 129-133, 1999.

2. Kaupmann, K., Malitschek, B., Schuler, V., Heid, J., Froestl, W., Beck, Pl, Mosbacher, J., Bischoff, S., Kulik, Á., Shigemoto, R., Karschin, A., Bettler, B.: GABAB-receptor subtypes assemble into functional heteromeric complexes.


Nature, 396, 683-687, 1998.

3. Kish, G., Módis, L., Hangody, L.: Osteochondral mosaicplasty for the treatment of focal chondral and osteochondral lesions of the knee and talus in the athlete.


Clin. Sports Med. 18, 45-66, 1999.

4. Kocsis, K., Hyttinen, M., Helminen, H.J., Aydelotte, M.B., Módis, L.: Combination of digital image analysis and polarization microscopy: theoretical considerations and experimental data.


Microsc. Res. Techn., 43, 511-517, 1998.

5. Polgár, E., Shehab, S.A.S., Watt, C., Todd, A.J.: GABAergic neurons that contain neuropeptide Y selectively target cells with the neurokinin 1 receptor in laminae III and IV of the rat spinal cord.


J. Neurosci. 19, 2637-2646, 1999.

6. Polgár, E., Fowler, J.H., McGill, M.M., Todd, A.J.: The types of neuron which contain protein kinase C gamma in rat spinal cord.


Brain Res., 833, 71-80, 1999.

7. Somogyvári, Z., Andai, A., Székely, Gy., Érdi, P.: On the role of self-excitation in the development of topographic order in the visual system of the frog.


BioSystems, 48, 215-222, 1998.

8. Székely, G.: Architecture of complexity in the nervous system.


In: 4th Systems Science European Congress, Ferrer, L. et al., Eds., Graficus Mari Montano, 581-589, 1999.



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