Rtecs number : ww2710000 chemical name : Talc (powder), containing no asbestos fibers

TALC

CHEMICAL NAME : Talc (powder), containing no asbestos fibers

CAS REGISTRY NUMBER : 14807-96-6

LAST UPDATED : 199907

DATA ITEMS CITED : 32

MOLECULAR FORMULA : H2-03-Si.3/4Mg

MOLECULAR WEIGHT : 96.33

WISWESSER LINE NOTATION : .MG4.SI-O3*3

COMPOUND DESCRIPTOR : Tumorigen

Natural Product

Primary Irritant

SYNONYMS/TRADE NAMES :

* Agalite

* Asbestine

* B 9

* B 13

* B 13 (mineral)

* CP 10-40

* CP 38-33

* Crystalite CRS 6002

* Desertalc 57

* Emtal 500

* Emtal 549

* Emtal 596

* Emtal 599

* EX-IT

* Fibrene C 400

* Finntalc M05

* Finntalc M15

* Finntalc P40

* Finntalc PF

* FW-XO

* LMR 100

* Micro Ace K1

* Micro Ace L1

* Micron White 5000A

* Micron White 5000P

* Micron White 5000S

* Microtalco IT Extra

* Mistron 139

* Mistron frost P

* Mistron RCS

* Mistron 2SC

* Mistron Star

* Mistron super frost

* Mistron vapor

* MP 12-50

* MP 25-38

* MP 40-27

* MP 45-26

* MST

* Nytal 200

* Nytal 400

* P 3

* PK-N

* Polytal 4641

* Polytal 4725

* Silicate: talc, containing no asbestos

* Steawhite

* Supreme

* Supreme dense

* Talc

* Talcron CP 44-31

* Talcum

* TY 80

** SKIN/EYE IRRITATION DATA **

TYPE OF TEST : Standard Draize test

ROUTE OF EXPOSURE : Administration onto the skin

SPECIES OBSERVED : Human

DOSE/DURATION : 300 ug/3D (Intermittent)

REACTION SEVERITY : Mild

REFERENCE :

85DKA8 "Cutaneous Toxicity, Proceedings of the 3rd Conference, 1976,"

Drill,

Volume(issue)/page/year: -,127,1977

** TUMORIGENIC DATA **

TYPE OF TEST : TCLo - Lowest published toxic concentration

ROUTE OF EXPOSURE : Inhalation

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 18 mg/m3/6H/2Y-I

TOXIC EFFECTS :

Tumorigenic - Carcinogenic by RTECS criteria

Lungs, Thorax, or Respiration - bronchiogenic carcinoma

Endocrine - tumors

REFERENCE :

NTPTR* National Toxicology Program Technical Report Series. (Research

Triangle Park, NC 27709) No.206- Volume(issue)/page/year:

NTP-TR-421,1993

TYPE OF TEST : TC - Toxic concentration (other than lowest)

ROUTE OF EXPOSURE : Inhalation

SPECIES OBSERVED : Rodent - rat

DOSE/DURATION : 11 mg/m3/1Y-I

TOXIC EFFECTS :

Tumorigenic - equivocal tumorigenic agent by RTECS criteria

Lungs, Thorax, or Respiration - tumors

REFERENCE :

43GRAK "Dusts and Disease, Proceedings of the Conference on Occupational

Exposures to Fibrous and Particulate Dust and Their Extension into the

Environment, 1977," Lemen, R., and J.M. Dement, eds., Park Forest South,

IL,

Pathotox Pub., 1979 Volume(issue)/page/year: -,389,1979

ACGIH TLV-Not classifiable as a human carcinogen

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

TLV/BEI,1997

ACGIH TLV-TWA 2 mg/m3, total dust

DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices

(BEIs) booklet issues by American Conference of Governmental Industrial

Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year:

TLV/BEI,1997

IARC Cancer Review:Animal Inadequate Evidence

IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of

Chemicals

to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY

12210)

IARC Cancer Review:Human Inadequate Evidence

IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of

Chemicals

to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY

12210)

IARC Cancer Review:Group 3

IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49

Sheridan Ave., Albany, NY 12210) No.1- 1979-

Volume(issue)/page/year:

7,349,1987

*** U.S. STANDARDS AND REGULATIONS ***

OSHA PEL (Gen Indu):8H TWA 20 mppcf, respirable dust

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

29,1910.1000,1994

OSHA PEL (Construc):8H TWA 20 mppcf, respirable dust

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

of Documents, Washington, DC 20402) Volume(issue)/page/year:

OSHA PEL (Shipyard):8H TWA 20 mppcf

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

29,1915.1000,1993

OSHA PEL (Fed Cont):8H TWA 20 mppcf, respirable dust

CFRGBR Code of Federal Regulations. (U.S. Government Printing Office,

Supt.

of Documents, Washington, DC 20402) Volume(issue)/page/year:

*** OCCUPATIONAL EXPOSURE LIMITS ***

OEL-AUSTRALIA:TWA 2.5 mg/m3 JAN 1993

OEL-AUSTRIA: MAK 5 mg/m3, JAN1999

OEL-BELGIUM:TWA 2 mg/m3 JAN 1993

OEL-FINLAND:TWA 5 mg/m3 JAN 1993

OEL-GERMANY:TWA 2 mg/m3 JAN 1993

OEL-SWITZERLAND:TWA 10 mg/m3 (total dust) JAN 1993

OEL-SWITZERLAND:TWA 2 mg/m3 (resp. dust) JAN 1993

OEL-UNITED KINGDOM:TWA 1 mg/m3 (resp. dust) JAN 1993

OEL-UNITED KINGDOM:TWA 10 mg/m3 (total dust) JAN 1993

OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV

OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV

*** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA ***

NIOSH RECOMMENDED EXPOSURE LEVEL (REL) :

NIOSH REL TO TALC (containing no asbestos)-air:10H 2 mg/m3

REFERENCE :

NIOSH* National Institute for Occupational Safety and Health, U.S. Dept.

of

Health, Education, and Welfare, Reports and Memoranda.

NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA :

NOHS - National Occupational Hazard Survey (1974)

NOHS Hazard Code - 71055

No. of Facilities: 38349 (estimated)

No. of Industries: 243

No. of Occupations: 149

No. of Employees: 527353 (estimated)

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - X9093

No. of Facilities: 273 (estimated)

No. of Industries: 2

No. of Occupations: 2

No. of Employees: 4245 (estimated)

No. of Female Employees: 590 (estimated)

NOES - National Occupational Exposure Survey (1983)

NOES Hazard Code - 71055

No. of Facilities: 82650 (estimated)

No. of Industries: 313

No. of Occupations: 192

No. of Employees: 1367384 (estimated)

No. of Female Employees: 348973 (estimated)

*** STATUS IN U.S. ***

EPA TSCA Section 8(b) CHEMICAL INVENTORY

EPA TSCA Section 8(d) unpublished health/safety studies

EPA TSCA TEST SUBMISSION (TSCATS) DATA BASE, JUNE 1999

NTP Carcinogenesis Studies (inhalation);clear evidence:rat

NTPTR* National Toxicology Program Technical Report Series. (Research

Triangle Park, NC 27709) No.206- Volume(issue)/page/year:

NTP-TR-421,1993

NTP Carcinogenesis Studies (inhalation);no evidence:mouse

NTPTR* National Toxicology Program Technical Report Series. (Research

Triangle Park, NC 27709) No.206- Volume(issue)/page/year:

NTP-TR-421,1993