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illiam WIJNS

Born September 26, 1951, Molenbeek (Belgium)

Present position and address

Co-Director, Cardiovascular Centre, O.L.V.Z. Aalst

Moorselbaan 164, B 9300 Aalst, Belgium


July 1976: Medical Doctor, U.C.L. (Grande Distinction)

1976 - 1981: Fellowship in Internal Medicine and Cardiology, St Luc University Hospitals, University of Louvain Medical School

July 1981: Certified Specialist in Internal Medicine

1981 - 1984: Thoraxcenter and Erasmus University, Rotterdam, The Netherlands

Feb 1983: Specialisten Registratie Commissie, The Netherlands

1984 - 1985: Research Fellowship, Division of Nuclear Medicine and Biophysics, University of California at Los Angeles (U.S.A.).

1986 - 1987: Social Service, Cardio-Pulmonary Physiopathology Unit, University of Louvain Medical School

ESC and other professional organisations

1992 - 1994: Secretary of the Working Group on Coronary Circulation of the European Society of Cardiology (ESC)

1994 - 1996: Vice-Chairman of the ESC Working Group on Coronary Circulation

1996 - 1998: Chairman of the ESC Working Group on Coronary Circulation

1996 - 2000: Member of the Executive Scientific Committee of the ESC

Chairman of the FOCUS sub-committee (1999-2000)

2000 - 2003: Chairman of the ESC Euro Heart Survey on Myocardial Revascularization

2002 - 2004: Chairman ESC Congress Programme Committee and Member of the ESC Board

2004 - 2006: Vice-President, External Relations, ESC

2006 – 2009 President, European Association of Percutaneous Cardiovascular
Interventions (EAPCI)
2006 - 2010: Board Member and Chair EU Relations Committee, European Society of
2006 – 2010: Board Member, World Heart Federation
Membership Scientific Societies: Belgian Society of Cardiology, American Heart Association (Fellow Circulation Council), Belgian Working Group on Interventional Cardiology, French Society of Cardiology (Membre Etranger), Euro PCR (member of Board Directors)
Membership Legal Authorities: Belgian Peer Review Council for Cardiology (2000 - 2006)

Editorial Boards

Editorial Board Member for European Heart Journal, EuroIntervention Journal, Dialogues in Cardiovascular Medicine, International Journal of Cardiac Imaging, International Journal of Cardiac Interventions, Italian Heart Journal.

Reviewer for American Journal of Cardiology, American Journal of Physiology, Circulation, Circulation Research, EuroIntervention Journal, European Heart Journal, Heart, Heart Drug, International Journal of Cardiac Imaging, International Journal of Cardiac Interventions, Journal of the American College of Cardiology, Journal of Nuclear Cardiology, Journal of Nuclear Medicine, The Lancet.


More than 300 publications in peer reviewed journals.

Reseach interest

Research efforts focus on the development and validation of innovative techniques in interventional cardiology such as intracoronary physiological measurements, drug-eluting stents and more recently, cell therapy and applications of multi-detector CT angiography.

Steering committees

1989 - ongoing: Steering Committee, Critical Event Committee member/chairman/principal investigator of various international multicenter clinical trials

1989 - 1995: Coordinator of the Cardiology Branch of the Concerted Action on "PET Investigations of Cellular Regeneration and Degeneration", sponsored by the European Community

2004: Member of the ESC Study Group on Stem Cells and Regeneration of the Heart

2006: Co-Chair ESC Task Force on drug-eluting stent safety

William Wijns, MD. PhD.


List of Publications


Book chapters

Lack of adaptation of pancreatic colipase in rats and mice.

Vandermeers-Piret MC, Vandermeers A, Wijns W, Rathé J, Christophe J.

Am J Physiol. 1977 Feb;232(2):E131-5.

Contrasting effect on cardiac output of digoxin and gitoxin in humans during congestive heart failure.

Col J, Wijns W, Brasseur L, Lesne M.

Int J Clin Pharmacol Ther Toxicol. 1981 Jul;19(7):314-8.
The effect of intracoronary thrombolysis with streptokinase on myocardial thallium distribution and left ventricular function assessed by blood-pool scintigraphy.

Simoons ML, Wijns W, Balakumaran K, Serruys PW, van den Brand M, Fioretti P, Reiber JH, Lie P, Hugenholtz PG.

Eur Heart J. 1982 Oct;3(5):433-40. No abstract available.
Clinical validation of fully automated computation of ejection fraction from gated equilibrium blood-pool scintigrams.

Reiber JH, Lie SP, Simoons ML, Hoek C, Gerbrands JJ, Wijns W, Bakker WH, Kooij PP.

J Nucl Med. 1983 Dec;24(12):1099-107.
Is transluminal coronary angioplasty mandatory after successful thrombolysis? Quantitative coronary angiographic study

Serruys PW, Wijns W, van den Brand M, Ribeiro V, Fioretti P, Simoons ML, Kooijman CJ, Reiber JH, Hugenholtz PG.

Br Heart J. 1983 Sep;50(3):257-65. No abstract available.
Pulmonary vascular tone is a determinant of basal lung perfusion in normal seated subjects.

Nemery B, Wijns W, Piret L, Caùwe F, Brasseur L, Frans A.

J Appl Physiol. 1983 Jan;54(1):262-6.
Prediction of mortality in hospital survivors of myocardial infarction. Comparison of predischarge exercise testing and radionuclide ventriculography at rest.

Fioretti P, Brower RW, Simoons ML, Das SK, Bos RJ, Wijns W, Reiber JH, Lubsen J, Hugenholtz PG.

Br Heart J. 1984 Sep;52(3):292-8.
Assessment of percutaneous transluminal coronary angioplasty by quantitative coronary angiography: diameter versus densitometric area measurements.

Serruys PW, Reiber JH, Wijns W, van den Brand M, Kooijman CJ, ten Katen HJ, Hugenholtz PG.

Am J Cardiol. 1984 Sep 1;54(6):482-8.
Left ventricular performance, regional blood flow, wall motion, and lactate metabolism during transluminal angioplasty.

Serruys PW, Wijns W, van den Brand M, Meij S, Slager C, Schuurbiers JC, Hugenholtz PG, Brower RW.

Circulation. 1984 Jul;70(1):25-36.
The exercise response in idiopathic dilated cardiomyopathy.

Kirlin PC, Das S, Zijnen P, Wijns W, Domenicucci S, Roelandt J, Pitt B.

Clin Cardiol. 1984 Apr;7(4):205-10.
Coronary artery dimensions from cineangiograms methodology and validation of a computer-assisted analysis procedure.

Reiber JH, Kooijman CJ, Slager CJ, Gerbrands JJ, Schuurbiers JC, Den Boer A, Wijns W, Serruys PW, Hugenholtz PG.

IEEE Trans Med Imaging. 1984;3(3):131-41.
Validation of radionuclide cardiac output measurements during exercise.

Melin JA, Wijns W, Robert A, Nannan M, De Coster P, Beckers C, Detry JM.

J Nucl Med. 1985 Dec;26(12):1386-93. Erratum in: J Nucl Med 1987 Mar;28(3):401-2.
Values and limitations of transstenotic pressure gradients measured during percutaneous coronary angioplasty.

Serruys PW, Wijns W, Reiber JH, de Feyter P, van den Brand M, Piscione F, Hugenholtz PG.

Herz. 1985 Dec;10(6):337-42.
Coronary angioplasty in myocardial infarction.

Wijns W, Serruys PW.

Am J Cardiol. 1985 Dec 1;56(15):1004. No abstract available.

Effects of short-term intravenous administration of diltiazem on left ventricular function and coronary hemodynamics in patients with coronary artery disease.

Serruys PW, Suryapranata H, Planellas J, Wijns W, Vanhaleweyk G, Jaski BE, Hugenholtz PG.

J Cardiovasc Pharmacol. 1985 Nov-Dec;7(6):1138-48.
Acute effects of intravenous nisoldipine on left ventricular function and coronary hemodynamics.

Serruys PW, Suryapranata H, Planellas J, Wijns W, Vanhaleweyk GL, Soward A, Jaski BE, Hugenholtz PG.

Am J Cardiol. 1985 Jul 1;56(1):140-6.
Alternative diagnostic strategies for coronary artery disease in women: demonstration of the usefulness and efficiency of probability analysis.

Melin JA, Wijns W, Vanbutsele RJ, Robert A, De Coster P, Brasseur LA, Beckers C, Detry JM.

Circulation. 1985 Mar;71(3):535-42.
Limitations of a QRS scoring system to assess left ventricular function and prognosis at hospital discharge after myocardial infarction.

Fioretti P, Brower RW, Lazzeroni E, Simoons ML, Wijns W, Reiber JH, Bos RJ, Hugenholtz PG.

Br Heart J. 1985 Mar;53(3):248-52.
Ventricular volumes during upright exercise.

Wijns W, Melin JA, Younis L, Detry JM.

Eur Heart J. 1985 Feb;6(2):185. No abstract available.

Assessment of short-, medium-, and long-term variations in arterial dimensions from computer-assisted quantitation of coronary cineangiograms.

Reiber JH, Serruys PW, Kooijman CJ, Wijns W, Slager CJ, Gerbrands JJ, Schuurbiers JC, den Boer A, Hugenholtz PG.

Circulation. 1985 Feb;71(2):280-8.
Quantitative angiography of the left anterior descending coronary artery: correlations with pressure gradient and results of exercise thallium scintigraphy.

Wijns W, Serruys PW, Reiber JH, van den Brand M, Simoons ML, Kooijman CJ, Balakumaran K, Hugenholtz PG.

Circulation. 1985 Feb;71(2):273-9.

Early detection of restenosis after successful percutaneous transluminal coronary angioplasty by exercise-redistribution thallium scintigraphy.

Wijns W, Serruys PW, Reiber JH, de Feyter PJ, van den Brand M, Simoons ML, Hugenholtz PG.

Am J Cardiol. 1985 Feb 1;55(4):357-61.

Predictive value of early maximal exercise test and thallium scintigraphy after successful percutaneous transluminal coronary angioplasty.

Wijns W, Serruys PW, Simoons ML, van den Brand M, de Feijter PJ, Reiber JH, Hugenholtz PG.

Br Heart J. 1985 Feb;53(2):194-200.

Radionuclide absolute left ventricular volumes during upright exercise: validation in normal subjects by simultaneous hemodynamic measurements.

Wijns W, Melin JA, Decoster PM, Piret LJ, Beckers C, Detry JM.

Eur J Nucl Med. 1985;10(3-4):111-7.

Early angiography after myocardial infarction: what have we learned?

de Feyter PJ, van den Brand M, Serruys PW, Wijns W.

Am Heart J. 1985 Jan;109(1):194-9. No abstract available.
Effect of intracoronary thrombolytic therapy on global and regional left ventricular function. A three year experience with randomization.

Serruys PW, Simoons ML, de Feyter PJ, Suryapranata H, Wijns W, van den Brand M, Planellas J, van Domburg R, Hugenholtz PG.

Z Kardiol. 1985;74 Suppl 6:117-27.
Elective PTCA of totally occluded coronary arteries not associated with acute myocardial infarction; short-term and long-term results.

Serruys PW, Umans V, Heyndrickx GR, van den Brand M, de Feyter PJ, Wijns W, Jaski B, Hugenholtz PG.

Eur Heart J. 1985 Jan;6(1):2-12.
Left ventricular function during transluminal angioplasty: a haemodynamic and angiographic study.

Serruys PW, Wijns W, van den Brand M, Mey S, Slager C, Schuurbiers JC, Hugenholtz PG, Brower RW.

Acta Med Scand Suppl. 1985;694:197-206. Review.
Long term improvement in global left ventricular function after early thrombolytic treatment in acute myocardial infarction. Report of a randomised multicentre trial of intracoronary streptokinase in acute myocardial infarction.

Res JC, Simoons ML, van der Wall EE, van Eenige MJ, Vermeer F, Verheugt FW, Wijns W, Braat S, Remme WJ, Serruys PW, et al.

Br Heart J. 1986 Nov;56(5):414-21.
Early changes in wall motion and wall thickness during percutaneous transluminal coronary angioplasty in man.

Serruys PW, Jaski B, Wijns W, Piscione F, ten Kate F, de Feyter P, van den Brand M, Hugenholtz PG.

Can J Cardiol. 1986 Jul;Suppl A:221A-232A.
Coronary angioplasty of the unstable angina related vessel in patients with multivessel disease.

de Feyter PJ, Serruys PW, Arnold A, Simoons ML, Wijns W, Geuskens R, Soward A, van den Brand M, Hugenholtz PG.

Eur Heart J. 1986 Jun;7(6):460-7.
Effects of intracoronary thrombolysis on global left ventricular function assessed by an automated edge detection technique.

van der Wall EE, Res JC, van Eenige MJ, Verheugt FW, Wijns W, Braat S, de Zwaan C, Remme WJ, Vermeer F, Reiber JH, et al.

J Nucl Med. 1986 Apr;27(4):478-83.
Preservation of global and regional left ventricular function after early thrombolysis in acute myocardial infarction.

Serruys PW, Simoons ML, Suryapranata H, Vermeer F, Wijns W, van den Brand M, Bär F, Zwaan C, Krauss XH, Remme WJ, et al.

J Am Coll Cardiol. 1986 Apr;7(4):729-42.
The haemodynamic and myocardial effects of dopexamine: a new beta 2-adrenoceptor and dopaminergic agonist.

Jaski BE, Wijns W, Foulds R, Serruys PW.

Br J Clin Pharmacol. 1986 Apr;21(4):393-400.
Effect of coronary occlusion during percutaneous transluminal angioplasty in humans on left ventricular chamber stiffness and regional diastolic pressure-radius relations.

Wijns W, Serruys PW, Slager CJ, Grimm J, Krayenbuehl HP, Hugenholtz PG, Hess OM.

J Am Coll Cardiol. 1986 Mar;7(3):455-63.

Ejection fraction response to upright exercise in hypertension: relation to loading conditions and to contractility.

Melin JA, Wijns W, Pouleur H, Robert A, Nannan M, De Coster PM, Beckers C, Detry JM.

Int J Cardiol. 1987 Oct;17(1):37-49.
Metabolic and ultrastructural abnormalities during ischemia in canine myocardium: noninvasive assessment by positron emission tomography.

Schwaiger M, Fishbein MC, Block M, Wijns W, Selin C, Phelps ME, Schelbert HR.

J Mol Cell Cardiol. 1987 Mar;19(3):259-69.
[Does a thrombocytopathy really exist in dominant exudative vitreoretinopathy?]

Cordonnier M, Wijns W, Bartik M, Verougstraete C.

Bull Soc Belge Ophtalmol. 1987;225 Pt 2:79-88. French. No abstract available.
Accumulation of polymorphonuclear leukocytes in reperfused ischemic canine myocardium: relation with tissue viability assessed by fluorine-18-2-deoxyglucose uptake.

Wijns W, Melin JA, Leners N, Ferrant A, Keyeux A, Rahier J, Cogneau M, Michel C, Bol A, Robert A, et al.

J Nucl Med. 1988 Nov;29(11):1826-32.

Assessment of thallium-201 redistribution versus glucose uptake as predictors of viability after coronary occlusion and reperfusion.

Melin JA, Wijns W, Keyeux A, Gurné O, Cogneau M, Michel C, Bol A, Robert A, Charlier A, Pouleur H.

Circulation. 1988 Apr;77(4):927-34.
Area-at-risk determination by technetium-99m-hexakis-2-methoxyisobutyl isonitrile in experimental reperfused myocardial infarction.

De Coster PM, Wijns W, Cauwe F, Robert A, Beckers C, Melin JA.

Circulation. 1990 Dec;82(6):2152-62.
Detection of restenosis after successful coronary angioplasty: improved clinical decision making with use of a logistic model combining procedural and follow-up variables.

Renkin J, Melin J, Robert A, Richelle F, Bachy JL, Col J, Detry JM, Wijns W.

J Am Coll Cardiol. 1990 Nov;16(6):1333-40.
Reversal of segmental hypokinesis by coronary angioplasty in patients with unstable angina, persistent T wave inversion, and left anterior descending coronary artery stenosis. Additional evidence for myocardial stunning in humans.

Renkin J, Wijns W, Ladha Z, Col J.

Circulation. 1990 Sep;82(3):913-21.
Angiographic evaluation of vasomotor properties of internal mammary arteries before and after coronary artery bypass grafting in men.

Hanet C, Wijns W, Decoster P, Pouleur H, Dion R, Rousseau MF.

Am J Cardiol. 1990 Apr 1;65(13):918-21. No abstract available.
Flow-induced vasomotor response to tachycardia of the human internal mammary artery and saphenous vein grafts late following bypass surgery.

Hanet C, Schroeder E, Michel X, Cosyns J, Dion R, Verhelst R, Wijns W.

Circulation. 1991 Nov;84(5 Suppl):III268-74.
Asynchronous (segmental early) relaxation impairs left ventricular filling in patients with coronary artery disease and normal systolic function.

Vanoverschelde JL, Wijns W, Michel X, Cosyns J, Detry JM.

J Am Coll Cardiol. 1991 Nov 1;18(5):1251-8.
Prevention of restenosis after percutaneous transluminal coronary angioplasty with thromboxane A2-receptor blockade. A randomized, double-blind, placebo-controlled trial. Coronary Artery Restenosis Prevention on Repeated Thromboxane-Antagonism Study (CARPORT).

Serruys PW, Rutsch W, Heyndrickx GR, Danchin N, Mast EG, Wijns W, Rensing BJ, Vos J, Stibbe J.

Circulation. 1991 Oct;84(4):1568-80.
Percutaneous transluminal coronary angioplasty of the left coronary artery in patients with chronic occlusion of the right coronary artery: clinical and functional results.

De Bruyne B, Renkin J, Col J, Wijns W.

Am Heart J. 1991 Aug;122(2):415-22.
Influence of balloon size and stenosis morphology on immediate and delayed elastic recoil after percutaneous transluminal coronary angioplasty.

Hanet C, Wijns W, Michel X, Schroeder E.

J Am Coll Cardiol. 1991 Aug;18(2):506-11.
Dominant exudative vitreoretinopathy: a sporadic case with a normal platelet aggregation study.

Cordonnier M, Wijns W, Bartik M, Van Nechel C, Verougstraete C.

Int Ophthalmol. 1991 Jul;15(4):223-7.
Angioplasty of coronary bifurcation stenoses: immediate and long-term results of the protecting branch technique.

Renkin J, Wijns W, Hanet C, Michel X, Cosyns J, Col J.

Cathet Cardiovasc Diagn. 1991 Mar;22(3):167-73.
Impaired left ventricular function in chronic coronary artery disease: distinction between necrotic and viable myocardium.

Depré C, Melin J, Wijns W.

Acta Clin Belg. 1991;46(1):1-6. No abstract available.
Vasomotor response to ergometrine and nitrates of saphenous vein grafts, internal mammary artery grafts, and grafted coronary arteries late after bypass surgery.

Hanet C, Robert A, Wijns W.

Circulation. 1992 Nov;86(5 Suppl):II210-6.
[Minimal hemorrhagic diathesis]

Huc N, Wijns W, Droeshout I, Capel P.

Rev Med Brux. 1992 Oct;13(8):307-8. French. No abstract available.
Hemodynamic and volume correlates of left ventricular diastolic relaxation and filling in patients with aortic stenosis.

Vanoverschelde JL, Essamri B, Michel X, Hanet C, Cosyns JR, Detry JM, Wijns W.

J Am Coll Cardiol. 1992 Oct;20(4):813-21.
Therapeutic dissection after successful coronary balloon angioplasty: no influence on restenosis or on clinical outcome in 693 patients. The MERCATOR Study Group (Multicenter European Research Trial with Cilazapril after Angioplasty to prevent Transluminal Coronary Obstruction and Restenosis).

Hermans WR, Rensing BJ, Foley DP, Deckers JW, Rutsch W, Emanuelsson H, Danchin N, Wijns W, Chappuis F, Serruys PW.

J Am Coll Cardiol. 1992 Oct;20(4):767-80.
One hundred and thirteen attempts at directional coronary atherectomy: the early and combined experience of two European centres using quantitative angiography to assess their results.

Umans V, Haine E, Renkin J, de Feyter P, Wijns W, Serruys PW.

Eur Heart J. 1992 Jul;13(7):918-24.
[Anti-phospholipid antibodies and recurrent miscarriage]

Capel P, Lambrechts A, Wijns W, Collard C.

Rev Med Brux. 1992 Apr;13(4):113-6. French.

Stenting of venous bypass grafts: a new treatment modality for patients who are poor candidates for reintervention.

de Scheerder IK, Strauss BH, de Feyter PJ, Beatt KJ, Baur LH, Wijns W, Heyndrix GR, Suryapranata H, van den Brand M, Buis B, et al.

Am Heart J. 1992 Apr;123(4 Pt 1):1046-54.
Regional oxidative metabolism in patients after recovery from reperfused anterior myocardial infarction. Relation to regional blood flow and glucose uptake.

Vanoverschelde JL, Melin JA, Bol A, Vanbutsele R, Cogneau M, Labar D, Robert A, Michel C, Wijns W.

Circulation. 1992 Jan;85(1):9-21.
Hemodynamic and mechanical determinants of myocardial O2 consumption in normal human heart: effects of dobutamine.

Vanoverschelde JL, Wijns W, Essamri B, Bol A, Robert A, Labar D, Cogneau M, Michel C, Melin JA.

Am J Physiol. 1993 Dec;265(6 Pt 2):H1884-92.
Luminal narrowing after percutaneous transluminal coronary angioplasty. A study of clinical, procedural, and lesional factors related to long-term angiographic outcome. Coronary Artery Restenosis Prevention on Repeated Thromboxane Antagonism (CARPORT) Study Group.

Rensing BJ, Hermans WR, Vos J, Tijssen JG, Rutch W, Danchin N, Heyndrickx GR, Mast EG, Wijns W, Serruys PW.

Circulation. 1993 Sep;88(3):975-85.
Effects of D-nebivolol and L-nebivolol on left ventricular systolic and diastolic function: comparison with D-L-nebivolol and atenolol.

Stoleru L, Wijns W, van Eyll C, Bouvy T, Van Nueten L, Pouleur H.

J Cardiovasc Pharmacol. 1993 Aug;22(2):183-90.
Optimal use of dobutamine stress for the detection and evaluation of coronary artery disease: combination with echocardiography or scintigraphy, or both?

Marwick T, D'Hondt AM, Baudhuin T, Willemart B, Wijns W, Detry JM, Melin J.

J Am Coll Cardiol. 1993 Jul;22(1):159-67.
Regional wall motion abnormalities in stunned and hibernating myocardium.

Heyndrickx GR, Wijns W, Melin JA.

Eur Heart J. 1993 Jul;14 Suppl A:8-13. Review.
Absence of detectable delayed elastic recoil 24 hours after percutaneous transluminal coronary angioplasty.

Hanet C, Michel X, Schroeder E, Wijns W.

Am J Cardiol. 1993 Jun 15;71(16):1433-6. No abstract available.
Diagnosis of coronary artery disease in elderly patients: safety and efficacy of dobutamine echocardiography.

Baudhuin T, Marwick T, Melin J, Wijns W, D'Hondt AM, Detry JM.

Eur Heart J. 1993 Jun;14(6):799-803.
Mechanisms of chronic regional postischemic dysfunction in humans. New insights from the study of noninfarcted collateral-dependent myocardium.

Vanoverschelde JL, Wijns W, Depré C, Essamri B, Heyndrickx GR, Borgers M, Bol A, Melin JA.

Circulation. 1993 May;87(5):1513-23.
The mechanism of directional coronary atherectomy.

Umans VA, Haine E, Renkin J, de Feyter PJ, Wijns W, Serruys PW.

Eur Heart J. 1993 Apr;14(4):505-10.
Recovery of regional contractile function and oxidative metabolism in stunned myocardium induced by 1-hour circumflex coronary artery stenosis in chronically instrumented dogs.

Heyndrickx GR, Wijns W, Vogelaers D, Degrieck Y, Bol A, Vandeplassche G, Melin JA.

Circ Res. 1993 Apr;72(4):901-13.
Competition between palmitate and ketone bodies as fuels for the heart: study with positron emission tomography.

Vanoverschelde JL, Wijns W, Kolanowski J, Bol A, Decoster PM, Michel C, Cogneau M, Heyndrickx GR, Essamri B, Melin JA.

Am J Physiol. 1993 Mar;264(3 Pt 2):H701-7.
Selection of the optimal nonexercise stress for the evaluation of ischemic regional myocardial dysfunction and malperfusion. Comparison of dobutamine and adenosine using echocardiography and 99mTc-MIBI single photon emission computed tomography.

Marwick T, Willemart B, D'Hondt AM, Baudhuin T, Wijns W, Detry JM, Melin J.

Circulation. 1993 Feb;87(2):345-54.
Patient, lesion, and procedural variables as risk factors for luminal re-narrowing after successful coronary angioplasty: a quantitative analysis in 653 patients with 778 lesions. Multicenter European Research Trial with Cilazapril after Angioplasty to prevent Transluminal Coronary Obstruction and Restenosis (MERCATOR) Study Group.

Hermans WR, Rensing BJ, Foley DP, Tijssen JG, Rutsch W, Emanuelsson H, Danchin N, Wijns W, Chappuis F, Serruys PW.

J Cardiovasc Pharmacol. 1993;22 Suppl 4:S45-57.

How accurate is dobutamine stress electrocardiography for detection of coronary artery disease? Comparison with two-dimensional echocardiography and technetium-99m methoxyl isobutyl isonitrile (mibi) perfusion scintigraphy.

Mairesse GH, Marwick TH, Vanoverschelde JL, Baudhuin T, Wijns W, Melin JA, Detry JM.

J Am Coll Cardiol. 1994 Oct;24(4):920-7.
On-line quantification of left ventricular volumes and ejection fraction by automated backscatter imaging-assisted boundary detection: comparison with contrast cineventriculography.

Vanoverschelde JL, Hanet C, Wijns W, Detry JM.

Am J Cardiol. 1994 Sep 15;74(6):633-5. No abstract available.
Comparative ability of dobutamine and exercise stress in inducing myocardial ischaemia in active patients.

Marwick TH, D'Hondt AM, Mairesse GH, Baudhuin T, Wijns W, Detry JM, Melin JA.

Br Heart J. 1994 Jul;72(1):31-8. Erratum in: Br Heart J 1994 Dec;72(6):590.
Relation between myocardial blood flow and the severity of coronary-artery stenosis.

Uren NG, Melin JA, De Bruyne B, Wijns W, Baudhuin T, Camici PG.

N Engl J Med. 1994 Jun 23;330(25):1782-8.
Assessment of left ventricular dysfunction by nuclear cardiology.

Melin JA, Wijns W, Vanoverschelde JL, Heyndrickx GR.

Cardiovasc Drugs Ther. 1994 May;8 Suppl 2:381-92. Review.
The use of carbon 11-labeled acetate for assessment of aerobic metabolism.

Melin JA, Vanoverschelde JL, Bol A, Heyndrickx G, Wijns W.

J Nucl Cardiol. 1994 Mar-Apr;1(2 Pt 2):S48-57. Review.
Coronary flow reserve calculated from pressure measurements in humans. Validation with positron emission tomography.

De Bruyne B, Baudhuin T, Melin JA, Pijls NH, Sys SU, Bol A, Paulus WJ, Heyndrickx GR, Wijns W.

Circulation. 1994 Mar;89(3):1013-22.
Clinical, histologic and quantitative angiographic predictors of restenosis after directional coronary atherectomy: a multivariate analysis of the renarrowing process and late outcome.

Umans VA, Robert A, Foley D, Wijns W, Haine E, de Feyter PJ, Serruys PW.

J Am Coll Cardiol. 1994 Jan;23(1):49-58.
Preoperative selection of patients with severely impaired left ventricular function for coronary revascularization. Role of low-dose dobutamine echocardiography and exercise-redistribution-reinjection thallium SPECT.

Vanoverschelde JL, Gerber BL, D'Hondt AM, De Kock M, Dion R, Wijns W, Melin JA.

Circulation. 1995 Nov 1;92(9 Suppl):II37-44.

Effect of aging on myocardial perfusion reserve.

Uren NG, Camici PG, Melin JA, Bol A, de Bruyne B, Radvan J, Olivotto I, Rosen SD, Impallomeni M, Wijns W.

J Nucl Med. 1995 Nov;36(11):2032-6.
Restenosis after coronary interventions and device specificity.

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