Acrin 6667 mri screening of the Contralateral Breast in Women with a Recent Diagnosis of Breast Cancer

The primary aim of this study is to determine the cancer yield of MRI in the contralateral breast of women with a recent breast cancer diagnosis and no known disease by mammography or clinical breast exam in the contralateral breast. A total of 1,000 women with a recent breast cancer diagnosis will be enrolled into the trial at 21 centers in the US, Canada and Germany. Women with a history of breast cancer, negative or benign mammogram, and negative or benign clinical breast exam of the contralateral breast within 90 days prior to the MRI will be invited to participate. All women will undergo MR evaluation of the contralateral breast. Truth regarding breast cancer status will be determined through the results of a breast biopsy, if that occurs, or as a result of a 24-month follow-up without clinical evidence of disease.