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X. D. Chen. The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes. Mol Cell Endocrinol. 2011; 342: 41-47. Chen xd


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陈小冬,副教授, 硕导



学 历

1994-1998 湖南农业大学 淡水渔业 本科

1998-2004 华中农业大学 生化与分子生物学 硕博连读

2003-2004 德国,做博士论文


职 历

2007.1至今 华中农业大学生命科学技术学院历任副教授

2004.7-2006.12 华中农业大学生命科学技术学院历任讲师



研究方向

动物脂肪代谢及其相关疾病的分子机理

主要兼职



电 话

027-87282669(O);18062420575

电子邮件

chenxd@mail.hzau.edu.cn

工作单位

华中农业大学生命科学技术学院生物技术系

研究成果

近期代表作:

  1. Y. Zhang, T. Lei, J.F. Huang, S.B. Wang, L.L. Zhou, Z.Q. Yang, X.D. Chen.The link between fibroblast growth factor 21 and sterol regulatory element binding protein 1c during lipogenesis in hepatocytes. Mol Cell Endocrinol. 2011; 342:41-47.

  2. Chen XD, Lei T, Xia T, Gan L, Yang ZQ. Increased expression of resistin and tumour necrosis factor-alpha in pig adipose tissue as well as effect of feeding treatment on resistin and cAMP pathway. Diabetes Obes Metab. 2004; 6:271-279.

  3. Chen XD, Chen YL, Wang SB, Lei T, Gan L, Yang ZQ. Molecular Characterization and functional analysis of porcine macrophage migration inhibitory factor (MIF) gene. Cytokine. 2010; 50: 84-90.

  4. Feng SQ, Chen XD, Xia T, Gan L, Dai MH, Qiu H, Peng Y, Lei T, Yang ZQ. Cloning, chromosome mapping and expression pattern of pig angptl3 and angptl4. Cytogenetic and Genome Research. 2006; 114: 44-49.

  5. Chen ZL, Lei T, Chen XD, Zhang J, Yu A, Long QQ, Long H, Jin D, Gan L, Yang ZQ. Porcine KLF gene family: Structure, mapping, and phylogenetic analysis. Genomics. 2010; 95: 111-119.

  6. Zhang J, Lei T, Chen XD, Peng Y, Long H, Zhou L, Huang J, Chen ZL, Long QQ, Yang ZQ. Resistin Up-Regulates COX-2 Expression via TAK1-IKK-NF-kappaB Signaling Pathway. Inflammation 2010; 33: 25-33.

  7. Peng Y, Lei T, Yuan JH, Chen XD, Long QQ, Zhan J, Lei P, Feng B, Yang ZQ. Arachidonic acid induces acetyl-CoA carboxylase 1 expression via activation of CREB1. Endocrine. 2009; Oct 20. [Epub ahead of print]

  8. Qiu H, Xia T, Chen XD, Zhao XL, Gan L, Feng SQ, Lei T, Yang ZQ. Cloning, comparative characterization of porcine SCAP gene, and identification of its two splice variants. Mol Genet Genomics. 2006; 276: 187-196.

  9. Dai MH, Xia T, Chen XD, Gan L, Feng SQ, Qiu H, Peng Y, Yang ZQ. Cloning and characterization of porcine resistin gene. Domest Anim Endocrinol. 2006; 30:88-97.

  10. Li YH, Lei T, Chen XD, Xia T, Peng Y, Long QQ, Zhang J, Feng SQ, Zhou L, Yang ZQ. Molecular cloning, chromosomal location and expression pattern of porcine CIDEa and CIDEc. Mol Biol Rep. 2009; 36:575-82.

  11. Qiu H, Xia T, Chen XD, Gan L, Feng SQ, Lei T, Dai MH, Yang ZQ. Characterization of pig INSIG1 and assignment to SSC18. Anim Genet. 2005; 36:284-286.

  12. Qiu H, Xia T, Chen XD, Feng SQ, Gan L, Lei T, Peng Y, Zhang GD, Nie T, Yue GP, Zhao XL, Yang ZQ. Sequencing and chromosome mapping of pig INSIG 2 and a related pseudogene. Anim Genet. 2005; 36:188-189.

  13. Zhou L, Xia T, Li Y, Chen XD, Peng Y, Yang ZQ. Transcriptional regulation of the resistin gene. Domest Anim Endocrinol. 2006; 30: 98-107.

  14. Jin D, Tan HJ, Lei T, Gan L, Chen XD, Long QQ, Feng B, Yang ZQ. Molecular cloning and characterization of porcine sirtuin genes. Comparative Biochemistry and Physiology, Part B 2009; 149: 348-358.

  15. Dai MH, Xia T, Zhang GD, Chen XD, Gan L, Feng SQ, Qiu H, Peng Y, Yang ZQ. Cloning, expression and chromosome localization of porcine adiponectin and adiponectin receptors genes. Domest Anim Endocrinol. 2006; 30: 117-125.

  16. Chen H, Xia T, Zhou L, Chen X, Gan L, Yao W, Peng Y, Yang Z. Gene organization, alternate splicing and expression pattern of porcine visfatin gene. Domest Anim Endocrinol. 2006; 32: 235-245.

  17. Zhou L, Li Y, Xia T, Feng S, Chen X, Yang Z. Resistin overexpression impaired glucose tolerance in hepatocytes. Eur Cytokine Netw. 2006;17:189-195.

  18. Yue GP, Du LR, Xia T, He XH, Qiu H, Xu LH, Chen XD, Feng SQ, Yang ZQ. One in vitro model for visceral adipose-derived fibroblasts in chronic inflammation. Biochem Biophys Res Commun. 2005; 333: 850-857.

  19. Nie T, Zhao XL, Qiu H, Xia T, Chen XD, Gan L, Feng SQ, Lei T, Dai MH, Yang ZQ. Sequencing analysis and map assignment of pig SREBF2 and ADFP gene. Anim Genet. 2005; 36:455-457.

  20. Lei T, Xia T, Gan L, Chen XD, Yuan JH,Zhu Y,Yang ZQ. Stage-specific Expression of Leukaemia Inhibitory Factor and its Receptor in Rabbit Pre-implantation Embryo and Uterine Epithelium During Early Pregnancy. Reproduction in Domestic Animals 2004; 39: 13–18.

  21. Chen H, Xia T, Zhou L, Chen X, Gan L, Yao W, Peng Y, Yang Z. Gene organization, alternate splicing and expression pattern of porcine visfatin gene. Domest Anim Endocrinol. 2007; 32: 235-245.

  22. Li X, Lei T, Xia T, Chen X, Feng S, Chen H, Chen Z, Peng Y, Yang Z. Molecular characterization, chromosomal and expression patterns of three aquaglyceroporins (AQP3, 7, 9) from pig. Comparative biochemistry and physiology B-Biochemistry &Molecular Biology 2008; 149: 468-476.

  23. Chen XD, Lei T, Xia T, Gan L, Yuan JH, Yang ZQ. Physiological Importance of Porcine TNF-Converting Enzyme for the Release of TNF-alpha in Obesity. 畜牧与兽医 2008;40:81 (会议摘要)

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