REFERENCES
1.Gal. I.: Vitamin A, pregnancy and oral contraceptives. Br. Med. I, 1974; 2:560
2.Briggs M.H., Briggs, M.: Vitamin C Requirement and oral contraceptives. Nature Vol. 238, 1972
3.Rose, D.P., Strong, R., Folikard. I; and Adams, P.W : Erythrocyte aminotransferaze activities in women using oral contraceptives. AM. I. Clin. Nutr. 1973; 26,48.
4.Lumerg, L; Cleary, R.E.; Ting-Kal, L : Effect of oral contraceptives on plasma concentration of pyridoxal phosphate; Am.I. Clin. Nutr. 1974; 27: 326.
5.Keshinro, 0.0. : The unconventional sources of ascorbic acid. Nutrition Reports International 1985.
6.Baker, H. and Frank, 0.: Clinical Vitaminology m"thods and Interpretation. Inter-science publishers N. York, 1968.
7.Roe, R.H. : Chemical determination of ascorbic acid, dehydroascorbic and diketegulonic acids. Methods of Biochemical Analysis, Vol. I, D. Glickedition Intersc. N. York, 1954; 134p.
8.Schwartze, M.A. and Williams, I.N. Inr. : New procedure for ascorbic acid analysis by Osazone method. Proc. Soc. Exp. BioI. Med. 1965; 88, 136.
9.Kofoed, M.A., Blumenkranze,N.B.; Houssay and Yamauchi,E. Y. : Cervical mucus and serum ascorbic acid and dehydroascorbic acid concentration during menstrual cycle. Am.I. Obset. Gynea. 1965; 91-95.
10.Dodds, M.L. : Sex as a factor in blood levels of ascorbic acid. I. Am. Dietet. 1969; 54-32.
UPDATE
AIDS CASE SURVEILLANCE IN ETHIOPIA: OCTOBER 31, 1993
National AIDS Control Programme
Ministry of Health
INTRODUCTION
This report is published by the Department of AIDS Control on a monthly basis. The major objectives of the publication are to:
* Notify the current status of AIDS epidemic in the country , and provide information which has prominence in decision making and future planning.
** Provide feedback to health institutions in the country.
From January 1986 to October 1993, a total or 8,622 AIDS cases have been reported by forty-eight hospitals in the country. Out of the total reported cases, about 42.1 % were residents of Addis Ababa. Other surveillance and research activities carried out in Ethiopia among different population groups have also indicated the extent of the HIV /AIDS epidemic and its progression.
2. Criteria used to diagnose AIDS patients in Ethiopia. The World Health Organization (WHO) provisional case definition with positive serology test for HIV antibodies is the criteria used to diagnose AIDS. According to the case definition, a patient has to manifest at least m1!igr and one minor signs and show and HIV Positive serology. (See page 9 of the report for the list of major and minor clinical symptoms/signs).
3. Summary of the report for the month of October, 1993. In October 1993 alone, a total of 246 AIDS cases were reported by 12 hospitals; 73 cases were from 5 Addis Ababa hospitals and the rest 173 cases were from 7 regional hospitals. The following table identifies the number of cases reported during this month, by reporting hospital and region/zone.
____________________________
NOTE:(I) You a~ kindly requested 10 share the information wid.
your staff. (2) Comments and suggestions are appreciated for
improving our reporting system
Table 1: Summary of AIDS Cases reported in Ethiopia, as of 31, October 1993.
Variable
|
Cumulative value
|
Number of AIDS cases reported
|
8.622
|
Number of reporting hospitals
|
48
|
Average (mean) delay of reporting in month
|
2
|
Average age of patients
|
30
|
Heterosexual transmission
|
85%
|
Sexually active age group (15-49)
|
94%
|
Proportion of married people
|
34%
|
Proportion of elderly (age >60 yrs).
|
0.8%
|
Proportion of paediatric cases (age <15 yrs)
|
1.5%
|
Male to Female ration of total cases
|
1.7:1
|
Patients residing in Addis Ababa
|
42%
|
Reported cases by A>A hospitals
|
53%
|
Major clinical symptoms
|
|
Weight Loss of > 10% body weight
|
92%
|
Prolonged Fever for > 1 months
|
87%
|
Chronic Diarrhoea for >1 month
|
66%
|
Persistent cough for > 1 month
|
69%
|
Note: See the full report for the details
Tale 2: Distribution of reported AIDS Cases by hospital, for the month October, 1993
|
|
Period of
|
Reported
|
Hospital
|
Region/Zone
|
Diagnosis
|
Cases
|
Alert
|
Addis Ababa
|
July 93-Sep.93
|
23
|
Central prison
|
“
|
Sep. 93
|
4
|
Kolfie TBC
|
“
|
Sep. 93-Oct. 93
|
5
|
St. Paulos
|
“
|
July 93-Oct. 93
|
29
|
Yekatit 12
|
“
|
Sep. 93
|
12
|
|
|
Sub Total =
|
73
|
Ambo
|
West Shoa
|
Aug. 93
|
13
|
Attat
|
West Shoa
|
Sep 93
|
13
|
Bushulo
|
Sidamo
|
Sep .93
|
11
|
Debre Berhan
|
North Shoa
|
Aug. 93
|
7
|
Dire Dawa
|
Dire Dawa
|
Aug 93
|
72
|
Hailemariam Mamo
|
East Shoa
|
July 93-Oct. 93
|
55
|
Wonji
|
East Shoa
|
Sep. 93
|
2
|
|
|
Sub Total =
|
173
|
|
|
Total =
|
246
|
Table 3: AIDS Cases by Quarter of Report.
Year-quarter
|
Males
|
Females
|
Total
|
Percent of Total Cases
|
86-1
|
1
|
0
|
1
|
0.01%
|
86-2
|
0
|
1
|
1
|
0.01%
|
87-1
|
4
|
0
|
4
|
0.05%
|
87-2
|
0
|
2
|
2
|
0.02%
|
87-3
|
2
|
2
|
4
|
0.05%
|
87-4
|
6
|
1
|
7
|
0.08%
|
88-1
|
4
|
3
|
7
|
0.08%
|
88-2
|
21
|
5
|
26
|
0.30%
|
88-3
|
19
|
4
|
23
|
0.27%
|
88-4
|
23
|
6
|
29
|
0.34%
|
89-1
|
11
|
4
|
15
|
0.17%
|
89-2
|
44
|
17
|
61
|
0.71%
|
89-3
|
21
|
16
|
37
|
0.43%
|
89-4
|
52
|
25
|
77
|
0.89%
|
90-1
|
49
|
27
|
76
|
0.88%
|
90-2
|
67
|
14
|
81
|
0.94%
|
90-3
|
92
|
49
|
141
|
1.64%
|
90-4
|
84
|
66
|
150
|
1.74%
|
91-1
|
218
|
82
|
300
|
3.48%
|
91-2
|
101
|
77
|
178
|
2.06%
|
91-3
|
161
|
80
|
241
|
2.80%
|
91-4
|
105
|
61
|
166
|
1.93%
|
92-1
|
145
|
108
|
253
|
2.93%
|
92-2
|
327
|
218
|
545
|
6.32%
|
92-3
|
603
|
397
|
1000
|
11.60%
|
92-4
|
909
|
549
|
1458
|
16.91%
|
93-1
|
618
|
403
|
1021
|
11.84%
|
93-2
|
528
|
294
|
822
|
9.53%
|
93-3
|
1030
|
620
|
1650
|
19.14%
|
93-4
|
148
|
98
|
246
|
2.85%
|
Total
|
5393
|
3229
|
8622
|
100.00%
|
AIDS case surveillance report in Ethiopia: October 31, 1993
Table 4: Distribution of AIDS Cases by Year of Report.
Year
|
Number
|
Sex Ratio
|
Percent of Total
|
|
Male
|
Female
|
Total
|
(M:F)
|
|
86
|
1
|
1
|
2
|
1:1
|
0.02%
|
87
|
12
|
5
|
17
|
2.4:1
|
0.20%
|
88
|
67
|
18
|
85
|
3.7:1
|
0.99%
|
89
|
128
|
62
|
190
|
2.1:1
|
2.20%
|
90
|
292
|
156
|
448
|
1.9:1
|
5.20%
|
91
|
585
|
300
|
885
|
1.9:1
|
10.26%
|
92
|
1984
|
1272
|
3256
|
1.6:1
|
37.76%
|
93
|
2324
|
1415
|
3739
|
1.6:1
|
43.37%
|
Total
|
5393
|
3229
|
8622
|
1.7:1
|
100.00%
|
`The proportion of female patients has increased since 1992.
Table 5: Age and Sex Distribution of reported AIDS Cases.
Age Group
|
Sex
|
|
|
|
Males
|
Females
|
Total
|
Percent
|
0-4
|
55
|
58
|
113
|
1.31%
|
5-14
|
8
|
6
|
14
|
0.16%
|
15-19
|
128
|
380
|
508
|
5.89%
|
20-29
|
2038
|
1760
|
3798
|
44.05%
|
30-39
|
1980
|
713
|
2693
|
31.23%
|
40-49
|
860
|
224
|
1084
|
12.57%
|
50-59
|
265
|
74
|
339
|
3.93%
|
60+
|
59
|
13
|
72
|
0.84%
|
Total
|
5393
|
3229
|
8622
|
100.00%
|
(Percent)
|
(62.55%)
|
(37.45%)
|
|
|
Average age for females
|
|
= 26.8 years,
|
|
|
“ “ males
|
|
=32.5 years,
|
|
|
“ “ both sex
|
|
=30..3 years.
|
|
|
(The bar chart is attached on the last page of this report).
Table 6: Distribution of Reported AIDS Cases by Marital Status
Marital Status:
|
Male
|
Female
|
Total
|
Percent of
|
Single
|
2474
|
1185
|
3659
|
42.33%
|
Married
|
2053
|
866
|
2919
|
33.86%
|
Divorced
|
293
|
715
|
1008
|
11.69%
|
Widowed
|
39
|
186
|
225
|
2.61%
|
Paediatric Cases
|
|
|
|
|
(Age< 15 years))
|
62
|
65
|
127
|
1.47%
|
Unspecified
|
472
|
211
|
683
|
8.04%
|
Total
|
5393
|
3229
|
8622
|
100.00%
|
Table 715> |