|Effect of Lycium barbarum Polysaccharides on Mortality of Drosophila melanogaster
Mentor: Mahtab Jafari
Lycium barbarum has been shown to have anti-aging properties, due to its anti-oxidative components. Previous studies have shown that the polysaccharides isolated from Lycium barbarum (LBP) have increased the maximal and average lifespan of Drosophila melanogaster. The intent of this study is to replicate experiments that have shown positive results in increasing the lifespan of fruit flies. It is hypothesized that LBP supplementation will decrease the mortality of fruit flies. Several doses (0.025, 0.050, 0.100, 0.125, 1.25, 12.5 mg/ml) of LBP were used in two mortality assays on fruit flies. These assays allowed us to determine the fraction dying of the LBP supplemented groups in relation to a control. Our results demonstrated that LBP supplementation decreased mortality in only male flies at 0.1 mg/mL.