ANEXO RIBIOFAR-1. Formulario de Incorporación de Grupos de Investigación en RIBIOFAR
Universidad/Institución/Entidad:
Universidade Federal de Santa Catarina
Facultad/Unidad:
Centro de Ciências Biológicas – Departamento de Farmacologia – Laboratório de Neurofarmacologia
Dirección completa (e-mail, postal, tel,):
Sala 308 – Bloco D – CCB – UFSC – Córrego Grande – Florianópolis – SC – 88040-900
Titulación Grado Area de Conocimiento Especialidad
Investigador Responsable
Thereza Christina Monteiro de Lima - Ph.D. – Biomédica – Farmacologia - Neuropsicofarmacologia
Miembros estables del Grupo:
Filipe Silveira Duarte
Ana Valquíria Calixto
Lígia Sena
Claves de Investigación:
Neurobiologia do stress, ansiedade e depressão
Validação de plantas medicinais com ação central
Actividades de Cooperación Iberoamericana:
Investigador Institución País Tema Número de Publicaciones
Sérgio Mora - Universidad de Chile – Chile – plantas ansiolíticas y antidepresivas – 1
Jaime Tortoriello – IMSS – México - plantas ansiolíticas y antidepresivas – 1
Maria del Carmen Ibarolla – Paraguay - plantas ansiolíticas y antidepresivas – 1
Publicaciones. Ejemplos representativos de los tres ultimos años:
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GAVIOLI E.C., MARZOLA G., GUERRINI R., BERTORELLI R., ZUCCHINI S., DE LIMA T.C.M., RAE G.A.,SALVADORI S., REGOLI D. & CALO’ G. Blockade of nociceptin/orphanin FQ – NOP receptor signalling produces antidepressant-like effects: pharmacological and genetic evidences from the mouse forced swimming test, European Journal of Neuroscience, 17: 1987-1990, 2003.
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GAVIOLI, E.C.; DUARTE, F.S.; BRESSAN, E.; FERRARA, P.; FARGES, R.C. & DE LIMA, T. C. M. Antidepressant-like effect of Ro5-4864, a peripheral-type benzodiazepine receptor ligand, in forced swimming test, European Journal of Pharmacology, 471: 21-26, 2003.
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TEIXEIRA, R.M. & DE LIMA, T.C.M. Involvement of tachykinin NK1 receptor in the behavioral and immunological responses to swimming stress in mice, Neuropeptides, 37: 307-315, 2003.
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GAVIOLI E.C.,VAUGHAN C.W., MARZOLA G., GUERRINI R., ZUCCHINI S., DE LIMA T.C.M., RAE G.A., CHRISTIE M.J., SALVADORI S., REGOLI D. & CALO’ G. Antidepressant-like effects of the nociceptin/orphanin FQ receptor antagonists UFP-101: new evidences in rats and mice, Naunyn-Schmiedeberg’s Archives of Pharmacology, 369: 547-553, 2004.
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DUARTE, F.S.; TESTOLIN, R. & DE LIMA, T.C.M. Further evidence on the anxiogenic-like effect of substance P evaluated in the elevated plus-maze in rats. Behavioural Brain Research, 154: 501-510, 2004.
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TEIXEIRA, R.M. & DE LIMA, T.C.M. Behavioral and immunological effects of substance P in female and male mice, Pharmacology, Biochemistry and Behavior, 79: 1-9, 2004 .
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LINO-DE-OLIVEIRA C.(PD), DE LIMA T.C.M., CAROBREZ A.P. Structure of the rat behaviour in the forced swimming stress. Behavioral Brain Research, 158(2):243-250, 2005.
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MORA, S, DIAZ-VELIZ, G., LUGENKRANZ, H., GARCIA-GONZÁLEZ, M., COTO-MORALES, T., POLETTI, C. (IC), DE LIMA, T. C. M., HERRERA-RUIZ, M. (D) AND TORTORIELLO, J. Behavioral central nervous system effects of the hydroalcoholic extract of Casimiroa edulis in rodents, Journal of Ethnopharmacology, 97(2):191-197, 2005.
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HELLION-IBARROLA MC, IBARROLA DA, MONTALBETTI Y, KENNEDY ML, HEINICHEN O, CAMPUZANO M, TORTORIELLO J, FERNANDEZ S, WASOWSKI C, MARDER M, DE LIMA TC, MORA S. The anxiolytic-like effects of Aloysia polystachya (Griseb.) Moldenke (Verbenaceae) in mice. Journal of Ethnopharmacology, 2005 (in press).
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COSTA EA, ROCHA FR, TORRES MLB, SOUCCAR C, DE LIMA TCM, LAPA AJ, LIMA-LANDMAN MTR, Behavioral effects of a neurotoxic compound isolated from Clibadium surinamense L (Asteraceae), Neurotoxicology and Teratology, 2005 (in press).
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DUARTE, FS, ANDRADE, ES, VIEIRA, RA, UEMURA, M, NUNES, RJ, DE LIMA, TCM. Synthesis and antidepressant-like action of stereoisomers of imidobenzenesulfonylaziridines in mice evaluated in the forced swimming test. Bioorganic and Medicinal Chemistry, 2005 (in press).
Equipos instrumentales y Bioensayos disponibles:
Testes comportamentais para diversas atividades centrais: esquiva passiva, labirinto em cruz e em T, hole-board, open-field, esterotáxico para cirurgias centrais, rota-rod, etc.
Necesidades y ofrecimientos de Cooperación:
No que seja necessário cooperar como sempre, treinamento, testes de atividade...
Financiación del grupo, magnitud anual y origen:
CNPq, FINEP e FAPESP
Fecha: 05/04/2006 |