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姓名:彭殿王

科部:胸腔部/臨床呼吸生理科



聯絡方式:

電話   02-28712121*7034

Email dwperng@vghtpe.gov.tw

學歷:

1997/09 - 2000/07 英國南安普敦大學醫學博士

1983/09 - 1990/06 中山醫學大學 醫學學士










經歷:

2013/09 - 臺北榮總胸腔部 臨床呼吸生理科主任

2011/12 - 2014/12 臺灣胸腔暨重症加護醫學會秘書長

2001/08 - 2013/08 臺北榮總呼吸加護中心主任

胸腔部 一般胸腔科 主治醫師

1996/10 - 1997/08 臺北榮總 胸腔部 主治醫師

1994/07 - 1996/10 臺北榮總 胸腔部 Research fellow

1991/06 - 1994/06 臺北榮總 內科部 住院醫師












研究方向:

了解呼吸道疾病的發炎機轉和修復過程,以及其治療方法相關的調節機制



五年內研究著作:

  1. Su VY, Chang YS, Hu YW, Hung MH, Ou SM, Lee FY, Chou KT, Yang KY, Perng DW, Chen TJ, Liu CJ. Carvedilol, Bisoprolol, and Metoprolol Use in Patients With Coexistent Heart Failure and Chronic Obstructive Pulmonary Disease. Medicine (Baltimore). 2016 Feb;95(5):e2427.

  2. Huang SF, Fung CP, Perng DW, Wang FD. Effects of corticosteroid and neuraminidase inhibitors on survival in patients with respiratory distress induced by influenza virus. J Microbiol Immunol Infect. 2015 Sep 9. pii: S1684-1182(15)00839-7.

  3. Su VY, Chen YT, Lin WC, Wu LA, Chang SCPerng DW, Su WJ, Chen YM, Chen TJ, Lee YC, Chou KT. Sleep Apnea and Risk of Panic Disorder. Ann Fam Med. 2015 Jul-Aug;13(4):325-30.

  4. Zhong N, Wang C, Zhou X, Zhang N, Humphries M, Wang L, Thach C, Patalano F, Banerji D; LANTERN Investigators. LANTERN: a randomized study of QVA149 versus salmeterol/fluticasone combination in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2015 Jun 5;10:1015-26.

  5. Su VY, Liu CJ, Hu YW, Su WJ, Chen YM, Lai SL, Chen TJ, Perng DW, Lee YC, Tzeng CH, Chou KT. Amyloidosis and the risk of cancer: a nationwide population-based study. Int J Clin Oncol. 2015 Dec;20(6):1244-51.

  6. Chou KT, Liu CC, Hsu HS, Chang SC, Chen YM, Perng DW, Hsu YT, Lee YC, Hung SC. Nocturnal stem cell mobilization in patients with obstructive sleep apnoea: a pilot study. Eur J Clin Invest. 2014 Dec;44(12):1189-96.

  7. Su VY, Liu CJ, Wang HK, Wu LA, Chang SC, Perng DW, Su WJ, Chen YM, Lin EY, Chen TJ, Chou KT. Sleep apnea and risk of pneumonia: a nationwide population-based study. CMAJ. 2014 Apr 1;186(6):415-21.

  8. Shih-Lung Cheng, Ming-Cheng Chan, Chin-Chou Wang, Ching-Hsiung Lin, Hao-Chien Wang, Jeng-Yuan Hsu, Liang-Wen Hang, Chee-Jen Chang, Diahn-Warng Perng, Chong-Jen Yu. COPD in Taiwan: a National Epidemiology Survey. International Journal of COPD. 2015:10(1) : 2459-2467

  9. An-Hsuan Lin, Meng-Han Liu, Hsin-Kuo Ko, Diahn-Warng Perng, Tzong-Shyuan Lee, and Yu Ru Kou1. Lung Epithelial TRPA1 Transduces the Extracellular ROS into Transcriptional Regulation of Lung Inflammation Induced by Cigarette Smoke: The Role of Influxed Ca2+. Mediators of Inflammation. 2015:148367.

  10. Chia-Lin Chou, Diahn-Warng Perng, Ting-Lun Lin, Anya Maan-Yuh Lin, Tzeng-Ji Chen, P Ming-Shan Wu, Yueh-Ching Chou. Analysis of Prescription Pattern and Guideline Adherence in the Management of Asthma among Medical Institutions and Physician Specialties in Taiwan between 2000-2010. Clinical Therateuics. 2015 Oct 1;37(10):2275-85.

  11. David Price, Aileen David-Wang, Sang-heon cho, James chung-Man ho, Jae-Won Jeong, chong-Kin liam, Jiangtao lin, Abdul razak Muttalif, Diahn-Warng Perng, Tze-lee Tan, Faisal Yunus, glenn neira. Time for a new language for asthma control: results from reAlise Asia. Journal of Asthma and Allergy. 2015 Sep 23;8:93-103.

  12. Lim S, Lam DC, Muttalif AR, Yunus F, Wongtim S, Lan le TT, Shetty V, Chu R, Zheng J, Perng DW, de Guia T. Impact of chronic obstructive pulmonary disease (COPD) in the Asia-Pacific region: the EPIC Asia population-based survey. Asia Pac Fam Med. 2015 Apr 23;14(1):4.

  13. Hsiao YH, Chen YT, Tseng CM, Wu LA, Lin WC, Su VY, Perng DW, Chang SC, Chen YM, Chen TJ, Lee YC, Chou KT. Sleep Disorders and Increased Risk of Autoimmune Diseases in Individuals without Sleep Apnea. Sleep. 2015 Apr 1;38(4):581-6.

  14. Lin CH, Hsu JY, Hsiao YH, Tseng CM, Su VY, Chen YH, Yang SN, Lee YC, Su KC, Perng DW(corresponding). Budesonide/formoterol maintenance and reliever therapy in asthma control: Acute, dose-related effects and real-life effectiveness Respirology. 2014 Nov 3

  15. Chou KT, Liu CC, Hsu HS, Chang SC, Chen YM, Perng DW, Hsu YT, Lee YC, Hung SC. Nocturnal Stem Cell Mobilization in Patients with Obstructive Sleep Apnea: A Pilot Study. Eur J Clin Invest. 2014 Oct 21.

  16. Cheng SL, Su KC, Wang HC, Perng DW(corresponding), Yang PC. Chronic obstructive pulmonary disease treated with inhaled medium- or high-dose corticosteroids: a prospective and randomized study focusing on clinical efficacy and the risk of pneumonia. Drug Des Devel Ther. 2014 May 28;8:601-7.

  17. Chou KT, Su KC, Huang SF, Hsiao YH, Tseng CM, Su VY, Hung SC, Perng DW(corresponding). Exhaled Nitric Oxide Predicts Eosinophilic Airway Inflammation in COPD. Lung. 2014 Aug;192(4):499-504.

  18. Huang CY, Chen YT, Wu LA, Liu CJ, Chang SC, Perng DW, Chen YM, Chen TJ, Lee YC, Chou KT. Sleep Apnoea Patients Have Higher Mortality When Confronting Sepsis. Eur J Clin Invest. 2013 Oct 9.

  19. Ching-Ming Tseng, Kuo-Ting Chang, Yi-Han Hsiao, Kang-Cheng Su, Yu-Chung Wu, Wen-Hu Hsu, Chun-Ming Tsai, Yu-Chin Lee, Diahn-Warng Perng (corresponding). The Suppression Effects of Thalidomide on Human Lung Fibroblasts: Cell Proliferation, Vascular Endothelial Growth Factor Release, and Collagen Production. Lung 2013 Aug;191(4):361-8.

  20. Tseng CM, Chen YT, Ou SM, Hsiao YH, Li SY, Wang SJ, Yang AC, Chen TJ, Perng DW (corresponding). The effect of cold temperature on increased exacerbation of chronic obstructive pulmonary disease: a nationwide study. PLoS One. 2013;8(3). Epub 2013 Mar 15.

  21. KC Su, YC Wu, CS Chen, MH Hung, YH Hsiao, CM Tseng, SC Chang, YC Lee, DW Perng (corresponding). Bile acids increase alveolar epithelial permeability via MAP kinase, cytosolic phospholipase A2, cyclooxygenase-2, PGE2, and junctional proteins. Respirology 2013 Jul;18(5):848-56.

  22. Perng DW, Chang TM, Wang JY, Lee CC, Lu SH, Shyue SK, Lee TS, Kou YR. Inflammatory role of AMP-activated protein kinase signaling in experimental model of toxic smoke inhalation injury. Critical Care Medicine. 2013 Jan;41(1):120-132.

  23. KT Chou, CS Chen, KC Su, MH Hung, YH Hsiao, CM Tseng, YM Chen, YC Lee, DW Perng (corresponding). Hospital outcomes for patients with Stage III and IV lung cancer admitted to the intensive care unit for sepsis-related acute respiratory failure. Journal of Palliative Medicine. 2012 Nov;15(11):1234-9. Epub 2012 Jul 25.

  24. Perng DW. Yang DM. Hsiao YH. Lo T. Lee Oscar. Wu MT. Wu YC. Lee YC. miRNA-146a expression positively regulates TNF-α-induced IL-8 production in mesenchymal stem cells and differentiated lung epithelial-like cells. Tissue Eng Part A. 2012 Nov;18(21-22):2259-67. Epub 2012 Sep 24.

  25. Perng DW, Su KC, Chou KT, Wu YC, Chen CS, Hsiao YH, Tseng CM, Chen YH, Hsueh TY, Lee YC. Long-acting β2 agonists and corticosteroids restore the reduction of histone deacetylase activity and inhibit H2O2-induced mediator release from alveolar macrophages. Pulm Pharmacol Ther. 2012 Aug;25(4):312-8. Epub 2012 Apr 21.

  26. Chou KT, Huang CC, Tsai DC, Chen YM, Perng DW, Shiao GM, Lee YC, Leu HB. Sleep Apnea and Risk of Retinal Vein Occlusion: A Nationwide Population-Based Study of Taiwanese. Am J Ophthalmol. 2012 Jul;154(1):200-205.e1. Epub 2012 Mar 30.

  27. Su KC, Tsai CC, Chou KT, Lu CC, Liu YY, Chen CS, Wu YC, Lee YC, Perng DW (correspondent). Spontaneous breathing trial needs to be prolonged in critically ill and elderly patients requiring mechanical ventilation. J Crit Care. 2012 Jun;27(3):324.e1-7. Epub 2011 Jul 27.

  28. Chou KT, Chang YT, Chen YM, Su KC, Perng DW, Chang SC, Shiao GM. The minimum period of polysomnography required to confirm a diagnosis of severe obstructive sleep apnoea. Respirology. 2011 Oct;16(7):1096-102.

  29. Perng DW, Chang KT, Su KC, Wu YC, Chen CS, Hsu WH, Tsai CM, Lee YC. Matrix metalloprotease-9 induces transforming growth factor-β(1) production in airway epithelium via activation of epidermal growth factor receptors. Life Sci. 2011 Jun 22.

  30. Chou KT, Huang CC, Chen YM, Perng DW, Chao HS, Chan WL, Leu HB. Asthma and Risk of Erectile Dysfunction-A Nationwide Population-Based Study. J Sex Med. 2011 Jun;8(6):1754-1760.

  31. Gastrointestinal Metastasis of Primary Lung Mucoepidermoid Carcinoma: A Case Report. CS Chen, DW Perng, YC Lee. Thorac Med 2011; 26: 99-103.

  32. Lee YC, Hung MH, Liu LY, Chang KT, Chou TY, Wang YC, Wu YC, Lai CL, Tsai CC, Su KC, Perng DW (first author and correspondent). The roles of transforming growth factor-β(1) and vascular endothelial growth factor in the tracheal granulation formation. Pulm Pharmacol Ther. 2011 Feb;24(1):23-31. Epub 2010 Nov 5.

  33. Tai HY, Tam MF, Chou H, Perng DW, Shen HD. Pen ch 13 Major Fungal Allergen Decreases CD44 Expression in Human Bronchial Epithelial Cells. Int Arch Allergy Immunol. 2010 Jun 17;153(4):367-371.

  34. Fang SY, Perng DW, Lee JY, Lin DY, Huang CY. An open-label, multicentre study of levocetirizine for the treatment of allergic rhinitis and urticaria in Taiwanese patients. Chin J Physiol. 2010 Aug 31;53(4):199-207.

研究室成員:吳默慈


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